Findings

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Evidence found and GRADE certainty

1,494 questions · 1,521 findings · 132 reviews · Hepato-Biliary

No studies found 303 · 19.9%GRADE not reported 39 · 2.6%Very low 876 · 57.6%Low 216 · 14.2%Moderate 65 · 4.3%High 22 · 1.4%

Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment

Adherance to treatment · participants with detectable HCV RNA after four weeks of treatment with pegylated interferon and ribavirin or participants with detectable…

Extended peginterferon plus ribavirin treatment for 72 weeks probably leads to lower adherance to treatment compared with standard peginterferon plus ribavirin treatment (moderate certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A (low risk of bias trials) Dienstag 1999 · patients with preventing hepatitis A.

The intervention leads to lower clinically apparent hepatitis A (low risk of bias trials) Dienstag… (high certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A (Dose of live attenuated HAV vaccine, titre < TCID50 ) all included trials Dienstag 1999 · patients with preventing hepatitis A.

It is very uncertain whether the intervention changes clinically apparent hepatitis A (Dose of live attenuated HAV… (very low certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A (low endemicity) low risk of bias Dienstag 1999 · patients with preventing hepatitis A.

The intervention leads to lower clinically apparent hepatitis A (low endemicity) low risk of bias… (high certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A (low endemicity) all included trials Dienstag 1999 · patients with preventing hepatitis A.

The intervention leads to lower clinically apparent hepatitis A (low endemicity) all included trials… (high certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A (high endemicity) low risk of bias Dienstag 1999 · patients with preventing hepatitis A.

The intervention leads to lower clinically apparent hepatitis A (high endemicity) low risk of bias… (high certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A (high endemicity) all included trials Dienstag 1999 · patients with preventing hepatitis A.

It is very uncertain whether the intervention changes clinically apparent hepatitis A (high endemicity) all included… (very low certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A (single dose regimen) low risk of bias Dienstag 1999 · patients with preventing hepatitis A.

The intervention leads to lower clinically apparent hepatitis A (single dose regimen) low risk of… (high certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A (single dose regimen) all included studies Dienstag 1999 · patients with preventing hepatitis A.

It is very uncertain whether the intervention changes clinically apparent hepatitis A (single dose regimen) all included… (very low certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A (multiple doses) low risk of bias Dienstag 1999 · patients with preventing hepatitis A.

The intervention leads to lower clinically apparent hepatitis A (multiple doses) low risk of bias… (high certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A (multiple doses) all included trials Dienstag 1999 · patients with preventing hepatitis A.

The intervention probably leads to lower clinically apparent hepatitis A (multiple doses) all included trials… (moderate certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A ( · patients with preventing hepatitis A.

The intervention leads to lower clinically apparent hepatitis A ( (high certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A (all included trials) Dienstag 1999 · patients with preventing hepatitis A.

It is very uncertain whether the intervention changes clinically apparent hepatitis A (all included trials) Dienstag 1999 (very low certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A ( · patients with preventing hepatitis A.

It is very uncertain whether the intervention changes clinically apparent hepatitis A ( (very low certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A ( · patients with preventing hepatitis A.

The intervention leads to lower clinically apparent hepatitis A ( (high certainty).

1 finding from 1 review

Intervention not reported

Clinicially apparent hepatitis A ( · patients with preventing hepatitis A.

It is very uncertain whether the intervention changes clinicially apparent hepatitis A ( (very low certainty).

1 finding from 1 review

Intervention not reported

Clinicially apparent hepatitis A ( · patients with preventing hepatitis A.

The intervention may leads to lower clinicially apparent hepatitis A ( (low certainty).

1 finding from 1 review

Intervention not reported

Clinically apparent hepatitis A ( · patients with preventing hepatitis A.

The intervention may leads to lower clinically apparent hepatitis A ( (low certainty).

1 finding from 1 review