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Evidence found and GRADE certainty

1,494 questions · 1,521 findings · 132 reviews · Hepato-Biliary

No studies found 303 · 19.9%GRADE not reported 39 · 2.6%Very low 876 · 57.6%Low 216 · 14.2%Moderate 65 · 4.3%High 22 · 1.4%

Parenteral nutrition plus branched‐chain‐amino‐acid‐enriched formula vs standard isotonic intravenous glucose solution

Mortality [within first 10 weeks after liver transplantation] · adult patients after liver transplantation.

Parenteral nutrition plus branched‐chain‐amino‐acid‐enriched formula showed no clear difference in mortality [within first 10 weeks after liver transplantation] compared with standard isotonic intravenous glucose solution (low certainty).

1 finding from 1 review

Standard parenteral nutrition vs standard isotonic intravenous glucose solution

Length of hospital stay after liver transplantation [days] · adult patients after liver transplantation.
2 findings from 1 review

Standard parenteral nutrition vs standard isotonic intravenous glucose solution

Mortality [within first 10 weeks after liver transplantation] · adult patients after liver transplantation.

Standard parenteral nutrition may leads to lower mortality [within first 10 weeks after liver transplantation] compared with standard isotonic intravenous glucose solution (low certainty).

1 finding from 1 review

Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment

Sustained virological response · participants with detectable HCV RNA after 12 weeks of treatment with pegylated interferon and ribavirin, but with >= 2 log viral…

It is very uncertain whether extended peginterferon plus ribavirin treatment for 72 weeks changes sustained virological response (SVR) compared with standard peginterferon plus ribavirin treatment (very low certainty).

1 finding from 1 review

Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment

Relapse · participants with detectable HCV RNA after 12 weeks of treatment with pegylated interferon and ribavirin, but with >= 2 log viral…

It is very uncertain whether extended peginterferon plus ribavirin treatment for 72 weeks changes relapse compared with standard peginterferon plus ribavirin treatment (very low certainty).

1 finding from 1 review

Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment

End of treatment response (ETR) · participants with detectable HCV RNA after 12 weeks of treatment with pegylated interferon and ribavirin, but with >= 2 log viral…

It is very uncertain whether extended peginterferon plus ribavirin treatment for 72 weeks changes end of treatment response (ETR) compared with standard peginterferon plus ribavirin treatment (very low certainty).

1 finding from 1 review

Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment

Sustained virological response · participants with detectable HCV RNA after four weeks of treatment with pegylated interferon and ribavirin

Extended peginterferon plus ribavirin treatment for 72 weeks may leads to higher sustained virological response (SVR) compared with standard peginterferon plus ribavirin treatment (low certainty).

1 finding from 1 review

Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment

Relapse · participants with detectable HCV RNA after four weeks of treatment with pegylated interferon and ribavirin

Extended peginterferon plus ribavirin treatment for 72 weeks may leads to lower relapse rate compared with standard peginterferon plus ribavirin treatment (low certainty).

1 finding from 1 review

Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment

End of treatment response (ETR) · participants with detectable HCV RNA after four weeks of treatment with pegylated interferon and ribavirin

Extended peginterferon plus ribavirin treatment for 72 weeks may leads to lower end of treatment response (ETR) compared with standard peginterferon plus ribavirin treatment (low certainty).

1 finding from 1 review