Findings

What do systematic reviews say?

671 questions · 731 findings · 61 reviews · Drugs and Alcohol

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No studies found 57 · 7.8%GRADE not reported 39 · 5.3%Very low 186 · 25.4%Low 239 · 32.7%Moderate 171 · 23.4%High 39 · 5.3%

Psychosocial interventions WITHOUT child involvement vs control

Frequency of alcohol misuse 12 months · Parents who use substances

1 finding from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 147 participants
Low

Psychosocial interventions WITHOUT child involvement vs control

Frequency of drug use 12 months · Parents who use substances

2 findings from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 196 participants
Low
Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 141 participants
Low

Psychosocial interventions vs control

Frequency of alcohol misuse 6 months · Mothers who use substances

1 finding from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 328 participants
Low

Psychosocial interventions vs control

Frequency of alcohol misuse 12 months · Mothers who use substances

1 finding from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 325 participants
Very low

Psychosocial interventions vs control

Frequency of drug use 12 months · Mothers who use substances

2 findings from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 484 participants
Low
Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 373 participants
Very low

Psychosocial interventions vs control

Frequency of alcohol misuse 6 months · Fathers who use substances

1 finding from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 147 participants
Low

Psychosocial interventions vs control intervention

Frequency of drug use 12 months · Parents who use substances

2 findings from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 625 participants
Moderate
Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 514 participants
Moderate

Psychosocial interventions vs control

Frequency of alcohol misuse 12 months · Fathers who use substances

1 finding from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 147 participants
Low

Psychosocial interventions vs control

Frequency of drug use 12 months · Fathers who use substances

2 findings from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 141 participants
Low
Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 141 participants
Low

Drug and alcohol use only‐focused psychosocial interventions vs control intervention

Frequency of alcohol misuse 6 months · Parents who use substances

1 finding from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 89 participants
Low

Drug and alcohol use only‐focused psychosocial interventions vs control intervention

Frequency of alcohol misuse 12 months · Parents who use substances

1 finding from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Low

Drug and alcohol use only‐focused psychosocial interventions vs control intervention

Frequency of drug use 12 months · Parents who use substances

2 findings from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 87 participants
Low
Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
Low

Parenting‐focused psychosocial interventions WITHOUT substance use‐focused component vs treatment

Frequency of alcohol misuse 6 months · Parents who use substances

1 finding from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 273 participants
Low

Methadone vs buprenorphine

Dropout · opiate‐dependent pregnant women

Methadone showed no clear difference in dropout rate compared with buprenorphine (moderate certainty).

1 finding from 1 review

Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
RR 0.66 [0.37, 1.2]
3 studies · 223 participants
Moderate

Methadone vs oral slow‐release morphine

Birthweight (g) · opiate‐dependent pregnant women

1 finding from 1 review

Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Low

Methadone vs oral slow‐release morphine

APGAR score (APGAR score ) · opiate‐dependent pregnant women

The review found no eligible studies for this question.

1 finding from 1 review

Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Methadone vs oral slow‐release morphine

Adverse events for the mother · opiate‐dependent pregnant women

1 finding from 1 review

Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Low

Methadone vs oral slow‐release morphine

Serious adverse events for the child · opiate‐dependent pregnant women

1 finding from 1 review

Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Low

Methadone vs buprenorphine

Use of Primary Substance · opiate‐dependent pregnant women

Methadone showed no clear difference in use of primary substance compared with buprenorphine (low certainty).

1 finding from 1 review

Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
RR 1.81 [0.7, 4.68]
2 studies · 151 participants
Low

Methadone vs buprenorphine

Birthweight (g) · opiate‐dependent pregnant women

1 finding from 1 review

Maintenance agonist treatments for opiate‐dependent pregnant women 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 19 participants
Very low