Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,494 questions · 1,521 findings · 132 reviews · Hepato-Biliary

No studies found 303 · 19.9%GRADE not reported 39 · 2.6%Very low 876 · 57.6%Low 216 · 14.2%Moderate 65 · 4.3%High 22 · 1.4%

Postoperative feeding via nasojejunal tube vs postoperative parenteral nutrition (PN)

All‐cause mortality · adult patients after liver transplantation.

It is very uncertain whether postoperative enteral nutrition (Osmolite) via nasojejunal tube changes mortality compared with postoperative parenteral nutrition (PN) (very low certainty).

1 finding from 1 review

Postoperative feeding via nasojejunal tube vs postoperative parenteral nutrition (PN)

Putative side effects of treatment (e.g. vomiting and diarrhoea) · adult patients after liver transplantation.

It is very uncertain whether postoperative enteral nutrition (Osmolite) via nasojejunal tube changes side effects (vomiting, diarrhoea) compared with postoperative parenteral nutrition (PN) (very low certainty).

1 finding from 1 review

Postoperative feeding via nasojejunal tube vs postoperative parenteral nutrition (PN)

Infection (overall) · adult patients after liver transplantation.

It is very uncertain whether postoperative enteral nutrition (Osmolite) via nasojejunal tube changes infection (overall) compared with postoperative parenteral nutrition (PN) (very low certainty).

1 finding from 1 review

Enteral nutrition via nasojejunal tube plus intravenous glutamine‐dipeptide supplementation vs parenteral nutrition

All‐cause mortality during hospital stay · adult patients after liver transplantation.

It is very uncertain whether enteral nutrition via nasojejunal tube plus intravenous… changes death (during length of initial hospital stay; ITT) compared with standard parenteral nutrition (very low certainty).

1 finding from 1 review

Enteral nutrition via nasojejunal tube plus intravenous glutamine‐dipeptide supplementation vs parenteral nutrition

Infection (ITT) ‐ mycotic infection · adult patients after liver transplantation.

It is very uncertain whether enteral nutrition via nasojejunal tube plus intravenous… changes infection (ITT) ‐ mycotic infection compared with standard parenteral nutrition (very low certainty).

1 finding from 1 review

Enteral nutrition via nasojejunal tube plus intravenous glutamine‐dipeptide supplementation vs parenteral nutrition

Infection (ITT) ‐ infection (overall) · adult patients after liver transplantation.

It is very uncertain whether enteral nutrition via nasojejunal tube plus intravenous… changes infection (ITT) ‐ infection (overall) compared with standard parenteral nutrition (very low certainty).

1 finding from 1 review

Enteral nutrition via nasojejunal tube plus intravenous glutamine‐dipeptide supplementation vs parenteral nutrition

Acute rejection · adult patients after liver transplantation.

It is very uncertain whether enteral nutrition via nasojejunal tube plus intravenous… changes acute rejection (ITT) compared with standard parenteral nutrition (very low certainty).

1 finding from 1 review

Parenteral nutrition with protein, fat, carbohydrates and branched‐chain amino acids vs 5% dextrose and normal saline

1‐year‐survival · adult patients after liver transplantation.

It is very uncertain whether parenteral nutrition with protein, fat, carbohydrates and… changes 1‐year‐survival compared with 5% dextrose and normal saline (very low certainty).

1 finding from 1 review

Hepatic product (HepaticAid) vs diet only (without supplement)

New onset of diabetes · adult patients with malnutrition and encephalopathy before and after liver transplantation.

It is very uncertain whether hepatic product (HepaticAid) changes new onset of diabetes compared with diet only (without supplement) (very low certainty).

1 finding from 1 review

Parenteral nutrition with protein, fat, carbohydrates and branched‐chain amino acids vs 5% dextrose and normal saline

3‐year‐survival · adult patients after liver transplantation.

It is very uncertain whether parenteral nutrition with protein, fat, carbohydrates and… changes 3‐year‐survival compared with 5% dextrose and normal saline (very low certainty).

1 finding from 1 review

Parenteral nutrition with alanyl‐glutamine, protein, fat, carbohydrates and branched‐chain amino acids vs 5% dextrose and normal saline

1‐year‐survival · adult patients after liver transplantation.

It is very uncertain whether parenteral nutrition with alanyl‐glutamine, protein, fat,… changes 1‐year‐survival compared with 5% dextrose and normal saline (very low certainty).

1 finding from 1 review

Parenteral nutrition with alanyl‐glutamine, protein, fat, carbohydrates and branched‐chain amino acids vs 5% dextrose and normal saline

3‐year‐survival · adult patients after liver transplantation.

It is very uncertain whether parenteral nutrition with alanyl‐glutamine, protein, fat,… changes 3‐year‐survival compared with 5% dextrose and normal saline (very low certainty).

1 finding from 1 review