Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,494 questions · 1,521 findings · 132 reviews · Hepato-Biliary

No studies found 303 · 19.9%GRADE not reported 39 · 2.6%Very low 876 · 57.6%Low 216 · 14.2%Moderate 65 · 4.3%High 22 · 1.4%

Intervention not reported

All‐cause mortality · people with chronic hepatitis C
1 finding from 1 review

Intervention not reported

Morbidity · people with chronic hepatitis C
1 finding from 1 review

Intervention not reported

Adverse events · people with chronic hepatitis C

It is very uncertain whether the intervention changes adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Failure of sustained virological response · people with chronic hepatitis C

The intervention showed no clear difference in failure of sustained virological response (low certainty).

1 finding from 1 review

Intervention not reported

Failure of virological end‐of‐treatment response · people with chronic hepatitis C

The intervention may leads to lower failure of virological end‐of‐treatment response (low certainty).

1 finding from 1 review

Intervention not reported

Participants without improvement in ALT and/or AST serum levels · people with chronic hepatitis C

The intervention showed no clear difference in participants without improvement in ALT and/or AST serum levels (low certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality · people with chronic hepatitis C
1 finding from 1 review

Intervention not reported

Chronic hepatitis C‐related mortality · people with chronic hepatitis C
1 finding from 1 review

Intervention not reported

Morbidity · people with chronic hepatitis C
1 finding from 1 review

Intervention not reported

Adverse events · people with chronic hepatitis C

It is very uncertain whether the intervention changes adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Failure of sustained virological response · people with chronic hepatitis C

The intervention showed no clear difference in failure of sustained virological response (low certainty).

1 finding from 1 review

Intervention not reported

Chronic hepatitis C‐related mortality · people with chronic hepatitis C
1 finding from 1 review

Intervention not reported

Failure of virological end‐of‐treatment response · people with chronic hepatitis C

The intervention may leads to lower failure of virological end‐of‐treatment response (low certainty).

1 finding from 1 review

Intervention not reported

Participants without improvement in ALT and/or AST serum levels · people with chronic hepatitis C
1 finding from 1 review

Intervention not reported

All‐cause mortality · people with chronic hepatitis C
1 finding from 1 review

Intervention not reported

Chronic hepatitis C‐related mortality · people with chronic hepatitis C
1 finding from 1 review

Intervention not reported

Morbidity · people with chronic hepatitis C
1 finding from 1 review

Intervention not reported

Adverse events · people with chronic hepatitis C

It is very uncertain whether the intervention changes adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Failure of sustained virological response · people with chronic hepatitis C

The intervention showed no clear difference in failure of sustained virological response (low certainty).

1 finding from 1 review