Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,562 questions · 1,645 findings · 107 reviews · Wounds

No studies found 651 · 39.6%GRADE not reported 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

foam dressing vs hydrocolloid dressing

Incidence of healing, short‐term · people of any age with an existing pressure ulcer of Category/Stage II or above

It is very uncertain whether foam dressings changes incidence of healing, short‐term compared with hydrocolloid dressings (very low certainty).

1 finding from 1 review

foam dressing vs hydrocolloid dressing

Adverse events, short‐term · people of any age with an existing pressure ulcer of Category/Stage II or above

It is very uncertain whether foam dressings changes adverse events, short‐term compared with hydrocolloid dressings (very low certainty).

1 finding from 1 review

foam dressing vs hydrogel dressing

Incidence of healing, short‐term · people of any age with an existing pressure ulcer of Category/Stage II or above

It is very uncertain whether foam dressing changes incidence of healing, short‐term compared with hydrogel dressing (very low certainty).

1 finding from 1 review

Intervention not reported

Proportion of wounds completely healed at 24 weeks · people with pressure ulcers

It is very uncertain whether the intervention changes proportion of wounds completely healed at 24 weeks (very low certainty).

1 finding from 1 review

Intervention not reported

Non‐serious adverse events · people with pressure ulcers

The intervention may leads to higher non‐serious adverse events (low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events · people with pressure ulcers

It is very uncertain whether the intervention changes serious adverse events (very low certainty).

1 finding from 1 review

Silver‐based antiseptics vs topical antibiotics

Time to complete healing · people with burns

Silver‐based antiseptics showed no clear difference in wound healing: time to complete healing (time‐to‐event data) compared with topical antibiotics (low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    HR 1.25 [0.94, 1.67]
    3 studies · 259 participants
    Low

Honey vs topical antibiotics

Peristent infection: honey versus SSD · people with burns

It is very uncertain whether honey changes peristent infection: honey versus SSD compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.1 [0.05, 0.19]
    2 studies · 170 participants
    Very low

Honey vs topical antibiotics

Adverse events: honey versus SSD · people with burns

It is very uncertain whether honey changes adverse events: honey versus SSD compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.2 [0.01, 3.97]
    3 studies · 250 participants
    Very low

Aloe vera vs topical antibiotics

Wound healing · people with burns

Aloe vera showed no clear difference in wound healing (number of healing events): Aloe Vera versus SSD compared with topical antibiotics (low certainty).

2 findings from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 1.41 [0.7, 2.85]
    1 study · 38 participants
    Low
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    3 studies · 210 participants
    Very low

Aloe vera vs topical antibiotics

Infection: Aloe Vera versus SSD · people with burns

It is very uncertain whether aloe vera changes infection: Aloe Vera versus SSD compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.93 [0.26, 3.34]
    3 studies · 221 participants
    Very low

Iodine vs topical antibiotics

Wound healing · people with burns

It is very uncertain whether iodine changes wound healing (mean time to healing) compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    2 studies · 148 participants
    Very low