Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,501 questions · 1,558 findings · 115 reviews · Vascular

No studies found 346 · 22.2%GRADE not reported 90 · 5.8%Very low 281 · 18%Low 477 · 30.6%Moderate 313 · 20.1%High 51 · 3.3%

Endovascular revascularisation plus conservative therapy vs conservative therapy

Secondary invasive interventions · intermittent claudication

Endovascular revascularisation plus conservative therapy leads to lower secondary invasive interventions compared with conservative therapy alone (high certainty).

1 finding from 1 review

Endovascular revascularisation vs conservative therapy

Maximum walking distance · intermittent claudication
2 findings from 1 review

IM injection vs IA injection

Wound/ulcer healing: number of participants with healing ulcer · people with critical limb ischaemia

IM injection showed no clear difference in wound/ulcer healing: number of participants with healing ulcer compared with IA injection (low certainty).

1 finding from 1 review