Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,923 questions · 1,956 findings · 143 reviews · Musculoskeletal

No studies found 555 · 28.4%GRADE not reported 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

Intervention not reported

Adverse events Participants (n) reported adverse effects · patients with treating osteoarthritis

The intervention showed no clear difference in adverse events Participants (n) reported adverse effects (low certainty).

1 finding from 1 review

Boswellia serrata vs valdecoxib

Adverse events Participants (n) reported adverse events · patients with treating osteoarthritis

It is very uncertain whether boswellia serrata changes adverse events Participants (n) reported adverse events compared with valdecoxib (very low certainty).

1 finding from 1 review

Boswellia serrata vs valdecoxib

Withdrawals due to adverse events · patients with treating osteoarthritis

It is very uncertain whether boswellia serrata changes adverse events Participants (n) withdrew due to adverse effects compared with valdecoxib (very low certainty).

1 finding from 1 review

Intervention not reported

Pain Global pain VAS 0‐100 (higher scores mean worse) · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Function Multiple tools4 · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported adverse events · patients with osteoarthritis

The intervention showed no clear difference in adverse events Participants (n) reported adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) withdrew due to adverse effects · patients with osteoarthritis

The intervention showed no clear difference in adverse events Participants (n) withdrew due to adverse effects (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) withdrew due to adverse effects · patients with treating osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis

The intervention showed no clear difference in adverse events Participants (n) reported serious adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Radiographic joint changes Change in Joint Space Width (JSW) from baseline (higher scores mean worse). · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Quality of life · patients with osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pain Global pain VAS 0‐100 (higher scores mean worse) · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Function Lequesne algofunctional index 0‐24 (higher scores mean worse) · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported adverse events · patients with osteoarthritis

The intervention showed no clear difference in adverse events Participants (n) reported adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) withdrew due to adverse effects · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis
1 finding from 1 review