Intervention not reported
Vector density · People at risk of CL or VL
1 finding from 1 review
- no estimate extracted1 study · 1 participantsLow
Findings
What do systematic reviews say?
1,444 questions · 1,518 findings · 135 reviews · Infectious Diseases
No studies found 135 · 8.9%GRADE not reported 150 · 9.9%Very low 350 · 23.1%Low 420 · 27.7%Moderate 321 · 21.1%High 142 · 9.4%
Intervention not reported
CL cases > 12 months · People at risk of CL or VL
The intervention may leads to lower CL cases > 12 months (low certainty).
1 finding from 1 review
- RR 0 [0, 0.49]1 study · 2938 participantsLow
Intervention not reported
VL cases > 2 years · People at risk of CL or VL
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Intervention not reported
Death or hospital admission · Children with anaemia
The intervention showed no clear difference in death or hospital admission (moderate certainty).
1 finding from 1 review
- Intermittent preventive antimalarial treatment for children with anaemia 2015 · Cochrane Headline outcomes onlyRR 0.9 [0.71, 1.13]3 studies · 3160 participantsModerate
Intervention not reported
Children with anaemia (Hb < 11 g/dL) · Children with anaemia
The intervention showed no clear difference in children with anaemia (Hb < 11 g/dL) (moderate certainty).
1 finding from 1 review
- Intermittent preventive antimalarial treatment for children with anaemia 2015 · Cochrane Headline outcomes onlyRR 0.97 [0.88, 1.07]4 studies · 2237 participantsModerate
Intervention not reported
Mean change in Hb from baseline · Children with anaemia
1 finding from 1 review
- Intermittent preventive antimalarial treatment for children with anaemia 2015 · Cochrane Headline outcomes onlyno estimate extracted4 studies · 1672 participantsModerate
Intervention not reported
Mean Hb · Children with anaemia
1 finding from 1 review
- Intermittent preventive antimalarial treatment for children with anaemia 2015 · Cochrane Headline outcomes onlyno estimate extracted4 studies · 1672 participantsLow
Artemisinin‐naphthoquine vs AL
Treatment failure at day 28 · adults and children with uncomplicated P falciparum malaria
Artemisinin‐naphthoquine showed no clear difference in treatment failure at day 28 compared with AL (low certainty).
1 finding from 1 review
- Artemisinin‐naphthoquine for treating uncomplicated Plasmodium falciparum malaria 2015 · Cochrane Headline outcomes onlyRR 1.02 [0.24, 4.37]3 studies · 487 participantsLow
Artemisinin‐naphthoquine vs AL
Treatment failure at day 42 · adults and children with uncomplicated P falciparum malaria
It is very uncertain whether artemisinin‐naphthoquine changes treatment failure at day 42 compared with AL (very low certainty).
1 finding from 1 review
- Artemisinin‐naphthoquine for treating uncomplicated Plasmodium falciparum malaria 2015 · Cochrane Headline outcomes onlyRR 0.09 [0, 1.59]1 study · 186 participantsVery low
Artemisinin‐naphthoquine vs DHA‐P
Treatment failure at day 28 · adults and children with uncomplicated P falciparum malaria
1 finding from 1 review
- Artemisinin‐naphthoquine for treating uncomplicated Plasmodium falciparum malaria 2015 · Cochrane Headline outcomes onlyno estimate extracted1 study · 143 participantsVery low
Artemisinin‐naphthoquine vs DHA‐P
Treatment failure at day 42 · adults and children with uncomplicated P falciparum malaria
It is very uncertain whether artemisinin‐naphthoquine changes treatment failure at day 42 compared with DHA‐P (very low certainty).
1 finding from 1 review
- Artemisinin‐naphthoquine for treating uncomplicated Plasmodium falciparum malaria 2015 · Cochrane Headline outcomes onlyRR 0.91 [0.13, 6.26]1 study · 143 participantsVery low
Praziquantel 40 mg/kg vs placebo
Parasitological failure At 1 to 2 months · people with urinary schistosomiasis
Praziquantel 40 mg/kg leads to lower parasitological failure At 1 to 2 months compared with placebo (high certainty).
1 finding from 1 review
- RR 0.42 [0.29, 0.59]7 studies · 864 participantsHigh
Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose
Adverse events: haematuria 12‐month · people with urinary schistosomiasis
It is very uncertain whether praziquantel 40 mg/kg single dose changes haematuria compared with 30 mg/kg single dose (very low certainty).
1 finding from 1 review
- RR 0.89 [0.47, 1.67]1 study · 117 participantsVery low
Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose
Proteinuria · people with urinary schistosomiasis
It is very uncertain whether praziquantel 40 mg/kg single dose changes proteinuria compared with 30 mg/kg single dose (very low certainty).
1 finding from 1 review
- RR 0.85 [0.34, 2.12]1 study · 117 participantsVery low
Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose
Adverse events · people with urinary schistosomiasis
1 finding from 1 review
- no estimate extracted8 studies · 992 participantsLow
Praziquantel 40 mg/kg multiple doses vs single dose
Parasitological failure At 2 years · patients with treating urinary schistosomiasis
It is very uncertain whether praziquantel 40 mg/kg multiple doses changes parasitological failure At 2 years compared with single dose (very low certainty).
1 finding from 1 review
- RR 2.71 [1.47, 5]1 study · 62 participantsVery low
Praziquantel 40 mg/kg multiple doses vs single dose
Mean percent egg reduction At 2 years · patients with treating urinary schistosomiasis
1 finding from 1 review
- no estimate extracted1 study · 62 participantsVery low
Praziquantel 40 mg/kg multiple doses vs single dose
Parasitological failure At 3 years · patients with treating urinary schistosomiasis
It is very uncertain whether praziquantel 40 mg/kg multiple doses changes parasitological failure At 3 years compared with single dose (very low certainty).
1 finding from 1 review
- RR 0.92 [0.59, 1.42]1 study · 43 participantsVery low
Praziquantel 40 mg/kg multiple doses vs single dose
Adverse events: haematuria 12‐month · patients with treating urinary schistosomiasis
It is very uncertain whether praziquantel 40 mg/kg multiple doses changes haematuria At 3 years compared with single dose (very low certainty).
1 finding from 1 review
- RR 0.7 [0.42, 1.17]1 study · 43 participantsVery low
Praziquantel 40 mg/kg multiple doses vs single dose
Adverse events · patients with treating urinary schistosomiasis
1 finding from 1 review
- no estimate extracted1 study · 43 participantsVery low