Intervention not reported
Test (measure and/or threshold)
1 finding from 1 review
no estimate extracted
95 participants
GRADE not reported
Intervention not reported
LACD (cut‐off: ≤25%)
1 finding from 1 review
no estimate extracted
108 participants
Moderate
Intervention not reported
Oblique flashlight test (grade 1)
1 finding from 1 review
no estimate extracted
72 participants
Low
Intervention not reported
SPAC (≤5 and/or S or P)
1 finding from 1 review
no estimate extracted
207 participants
Moderate
Intervention not reported
Scheimpflug photography (ACD central)
1 finding from 1 review
no estimate extracted
126 participants
Moderate
Intervention not reported
AS‐OCT (subjective assessment)
1 finding from 1 review
no estimate extracted
270 participants
Moderate
Proportion of participants with re‐epithelialization and complete healing with or without scar formation at 4 to 8 weeks Assessed by slit‐lamp biomicroscopy · participants of any age with confirmed cases of bacterial keratitis
1 finding from 1 review
no estimate extracted
15 participants
Very low
Proportion of participants with BCVA of 20/100 or better at 4 to 8 weeks Assessed using a logMAR chart · participants of any age with confirmed cases of bacterial keratitis
1 finding from 1 review
no estimate extracted
12 participants
Very low
Mean change from baseline in BCVA at 4 to 8 weeks Assessed using a logMAR chart · participants of any age with confirmed cases of bacterial keratitis
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Proportion of participants with a reduction in corneal infiltrate at 4 to 8 weeks Assessed by outcome assessors · participants of any age with confirmed cases of bacterial keratitis
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Proportion of participants with reduction in intraocular inflammation at 4 to 8 weeks Assessed by corneal keratic precipitates, anterior chamber cellular reaction, or other appropriate measure · participants of any age with confirmed cases of bacterial keratitis
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Proportion of participants with treatment failure at 4 to 8 weeks Assessed by outcome assessors · participants of any age with confirmed cases of bacterial keratitis
1 finding from 1 review
Proportion of participants with adverse events at 4 to 8 weeks Assessed by outcome assessors · participants of any age with confirmed cases of bacterial keratitis
1 finding from 1 review
Change in BCVA from baseline to 24 months · adults with GA due to AMD
1 finding from 1 review
Proportion of participants losing ≥ 10 EDTRS letters · adults with GA due to AMD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Progression of geographic atrophy · adults with GA due to AMD
1 finding from 1 review
Advanced AMD · adults with GA due to AMD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mean change in macular sensitivity · adults with GA due to AMD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · adults with GA due to AMD
1 finding from 1 review
Proportion of participants losing ≥ 15 EDTRS letters · adults with GA due to AMD
Emixustat showed no clear difference in proportion of participants losing ≥ 15 EDTRS letters at 24 months** compared with placebo (low certainty).
1 finding from 1 review