Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,060 questions · 1,105 findings · 84 reviews · Metabolic and Endocrine Disorders

No studies found 434 · 39.3%GRADE not reported 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%

Intervention not reported

Myocardial infarction (fatal and non‐fatal) (ticlopidine vs placebo) · patients with type 2 diabetes mellitus

The intervention showed no clear difference in myocardial infarction (fatal and non‐fatal) (ticlopidine vs placebo) (moderate certainty).

1 finding from 1 review

Intervention not reported

Stroke (fatal and non‐fatal) (a. ticlopidine vs aspirin) (b. clopidogrel vs aspirin & dipyramidole) · patients with type 2 diabetes mellitus

The intervention probably leads to lower stroke (fatal and non‐fatal) (a. ticlopidine vs aspirin) (b.… (moderate certainty).

1 finding from 1 review

Intervention not reported

Death from any cause ( · patients with diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Morbidity ( · patients with diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Health‐related quality of life ( · patients with diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events ( · patients with diabetes mellitus
1 finding from 1 review

Intervention not reported

Costs ( · patients with diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

HbA1c ( · patients with diabetes mellitus

The intervention showed no clear difference in hbA1c ( (moderate certainty).

1 finding from 1 review