Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,495 questions · 1,554 findings · 140 reviews · Heart

No studies found 272 · 17.5%GRADE not reported 44 · 2.8%Very low 329 · 21.2%Low 464 · 29.9%Moderate 319 · 20.5%High 126 · 8.1%

Transradial vs transfemoral approach

Short‐term NACE · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial probably leads to lower short‐term NACE compared with transfemoral approach (moderate certainty).

1 finding from 1 review

Transradial vs transfemoral approach

Short‐term cardiac death · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial probably leads to lower short‐term cardiac death compared with transfemoral approach (moderate certainty).

1 finding from 1 review

Transradial vs transfemoral approach

Short‐term MI · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial showed no clear difference in short‐term MI compared with transfemoral approach (high certainty).

1 finding from 1 review

Transradial vs transfemoral approach

Success of the procedure · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial probably leads to lower success of the procedure compared with transfemoral approach (moderate certainty).

1 finding from 1 review

Transradial vs transfemoral approach

Short‐term all‐cause mortality · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial leads to lower short‐term all‐cause mortality compared with transfemoral approach (high certainty).

1 finding from 1 review

Transradial vs transfemoral approach

Access site complications · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial may leads to lower access site complications compared with transfemoral approach (low certainty).

1 finding from 1 review

Higher polyunsaturated fatty acid (PUFA) vs lower PUFA

Major adverse cardiac and cerebrovascular events · people with or without existing CVD, men and women

It is very uncertain whether higher polyunsaturated fatty acid (PUFA) changes major adverse cardiac and cerebrovascular events compared with lower PUFA (very low certainty).

1 finding from 1 review

Higher polyunsaturated fatty acid (PUFA) vs lower PUFA

Cardiovascular events · people with or without existing cardiovascular disease, men and women

Higher polyunsaturated fatty acid (PUFA) showed no clear difference in cardiovascular events compared with lower PUFA (moderate certainty).

1 finding from 1 review

Higher polyunsaturated fatty acid (PUFA) vs lower PUFA

Coronary heart disease mortality – CHD deaths · people with or without existing cardiovascular disease, men and women

Higher polyunsaturated fatty acid (PUFA) showed no clear difference in coronary heart disease mortality compared with lower PUFA (low certainty).

1 finding from 1 review

Higher polyunsaturated fatty acid (PUFA) vs lower PUFA

Atrial fibrillation and arrhythmias · people with or without existing cardiovascular disease, men and women

It is very uncertain whether higher polyunsaturated fatty acid (PUFA) changes atrial fibrillation and arrhythmias compared with lower PUFA (very low certainty).

1 finding from 1 review