Lithium vs haloperidol
It is very uncertain whether lithium changes acceptability: total withdrawals compared with haloperidol (very low certainty).
- OR 0.29 [0.03, 3.12]1 study · 30 participantsVery low
It is very uncertain whether lithium changes acceptability: total withdrawals compared with haloperidol (very low certainty).
The review found no eligible studies for this question.
It is very uncertain whether lithium changes efficacy: response (categorical) BMRS change ≥ 50% from baseline to… compared with zuclopenthixol (very low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Lithium leads to higher adverse event: tremor compared with placebo (high certainty).
It is very uncertain whether lithium changes acceptability: total withdrawals compared with zuclopenthixol (very low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Lithium showed no clear difference in efficacy: remission (categorical) YMRS ≤ 12/absence of DSM‐IV mania… compared with risperidone (low certainty).
Lithium probably leads to higher acceptability: total withdrawals compared with risperidone (moderate certainty).
Lithium probably leads to lower adverse events: drowsiness/ somnolence compared with risperidone (moderate certainty).
The review found no eligible studies for this question.
Lithium showed no clear difference in efficacy: response (continuous) YMRS change by ≥ 50% at end of study compared with aripiprazole (moderate certainty).
Lithium showed no clear difference in efficacy: remission (categorical) YMRS ≤ 12 at end of study compared with aripiprazole (moderate certainty).
Lithium leads to higher adverse event: somnolence compared with placebo (high certainty).
Lithium showed no clear difference in acceptability: total withdrawals compared with aripiprazole (moderate certainty).
Lithium showed no clear difference in adverse events: tremor compared with aripiprazole (moderate certainty).
Lithium showed no clear difference in adverse events: somnolence/sedation compared with aripiprazole (moderate certainty).