Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,060 questions · 1,105 findings · 84 reviews · Metabolic and Endocrine Disorders

No studies found 434 · 39.3%GRADE not reported 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%

Intensive glycaemic control vs conventional glucose control

All‐cause mortality · patients with type 2 diabetes mellitus

Intensive glycaemic control showed no clear difference in all‐cause mortality compared with conventional glycaemic control (moderate certainty).

1 finding from 1 review · compare the 2 reviews

Intensive glycaemic control vs conventional glucose control

Cardiovascular mortality · patients with type 2 diabetes mellitus

Intensive glycaemic control showed no clear difference in cardiovascular mortality compared with conventional glycaemic control (moderate certainty).

1 finding from 1 review

Intensive glycaemic control vs conventional glucose control

Non‐fatal MI · patients with type 2 diabetes mellitus

Intensive glycaemic control probably leads to lower non‐fatal myocardial infarction compared with conventional glycaemic control (moderate certainty).

1 finding from 1 review

Intensive glycaemic control vs conventional glucose control

End‐stage renal disease · patients with type 2 diabetes mellitus

Intensive glycaemic control showed no clear difference in end‐stage renal disease compared with conventional glycaemic control (moderate certainty).

1 finding from 1 review

Intervention not reported

Diabetes and non‐diabetes related morbidity · peri‐ or postmenopausal women with type 1 diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Death from any cause · peri‐ or postmenopausal women with type 1 diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Health‐related quality of life · peri‐ or postmenopausal women with type 1 diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review