Toxicity: grade 3 or 4 fatigue · treatment of relapsed epithelial ovarian cancer
It is very uncertain whether EGFR tyrosine kinase inhibitor (TKI) plus chemotherapy changes toxicity: grade 3 or 4 fatigue compared with chemotherapy alone (very low certainty).
1 finding from 1 review
Toxicity: cardiac toxicity (any grade) · treatment of relapsed epithelial ovarian cancer
EGFR tyrosine kinase inhibitor (TKI) plus chemotherapy showed no clear difference in toxicity: cardiac toxicity (any grade) compared with chemotherapy alone (low certainty).
1 finding from 1 review
Overall survival ( · people with HGG
Anti‐angiogenic therapy showed no clear difference in overall survival ( compared with no anti‐angiogenic therapy (high certainty).
4 findings from 1 review
HR 0.95 [0.88, 1.02]
11 studies · 3743 participants
High
HR 0.93 [0.86, 1.02]
8 studies · 2833 participants
High
HR 0.99 [0.85, 1.16]
3 studies · 910 participants
Moderate
Show 1 more finding
Progression‐free survival · people with HGG
Anti‐angiogenic therapy leads to lower progression‐free survival ( compared with no anti‐angiogenic therapy (high certainty).
4 findings from 1 review
HR 0.73 [0.68, 0.79]
10 studies · 3595 participants
High
HR 0.75 [0.69, 0.82]
8 studies · 2833 participants
High
HR 0.64 [0.54, 0.76]
2 studies · 762 participants
Moderate
Show 1 more finding
Rate of symptom relief · women previously treated for endometrial cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Rate of tumour recurrence · women previously treated for endometrial cancer
It is very uncertain whether oestrogen replacement therapy changes rate of tumour recurrence compared with placebo (very low certainty).
1 finding from 1 review
Rate of appearance of a new malignancy · women previously treated for endometrial cancer
It is very uncertain whether oestrogen replacement therapy changes rate of appearance of a new malignancy compared with placebo (very low certainty).
1 finding from 1 review
Rate of survival: overall survival · women previously treated for endometrial cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Progression‐free survival (PSF) · women previously treated for endometrial cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Diarrhoea · participants with cancer treated with radiotherapy (with or without chemotherapy)
1 finding from 1 review
Diarrhoea · participants with cancer treated with chemotherapy
Probiotics may leads to lower any diarrhoea compared with placebo (low certainty).
1 finding from 1 review
Quality of life ‐ not measured · participants with cancer treated with chemotherapy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Diarrhoea (grade 2+) · participants with cancer treated with chemotherapy
Probiotics showed no clear difference in diarrhoea grade 2 or higher compared with placebo (low certainty).
1 finding from 1 review
Grade 3 to 4 diarrhoea · participants with cancer treated with chemotherapy
Probiotics showed no clear difference in diarrhoea grade 3 or higher compared with placebo (low certainty).
1 finding from 1 review
Diarrhoea grade 4 · participants with cancer treated with chemotherapy
Probiotics showed no clear difference in diarrhoea grade 4 compared with placebo (low certainty).
1 finding from 1 review
Time to rescue medication ‐ not measured · participants with cancer treated with chemotherapy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Requiring rescue medication for diarrhoea · participants with cancer treated with chemotherapy
1 finding from 1 review
Adverse events · participants with cancer treated with chemotherapy
1 finding from 1 review
All‐cause mortality · participants with cancer treated with chemotherapy
1 finding from 1 review
Diarrhoea · participants with cancer treated with radiotherapy (with or without chemotherapy)
It is very uncertain whether probiotics changes any diarrhoea compared with other active treatment (very low certainty).
1 finding from 1 review