Surgery for glaucoma ‐ 24 months · macular edema in diabetes
Intravitreal fluocinolone acetonide implant 0.19 mg may leads to higher surgery for glaucoma ‐ 24 months compared with sham (low certainty).
1 finding from 1 review
Visual acuity · macular edema in diabetes
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Gain 3+ lines of visual acuity at 1 year · macular edema in diabetes
Intravitreal dexamethasone implant 0.7 mg showed no clear difference in gain of three or more lines visual acuity ‐ 12 months compared with sham (moderate certainty).
1 finding from 1 review
Gain of 3 or more lines of visual acuity · macular edema in diabetes
It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes gain of three or more lines visual acuity ‐ 24 months** compared with sham (very low certainty).
1 finding from 1 review
RR 4.12 [0.48, 34.99]
Studies not reported
Very low
Change in retinal thickness (micron) (negative is better) · macular edema in diabetes
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Cataract progression ‐ 24 months · macular edema in diabetes
Intravitreal triamcinolone acetonide injection 4 mg showed no clear difference in cataract progression ‐ 24 months compared with sham (low certainty).
1 finding from 1 review
RR 3 [0.97, 9.3]
Studies not reported
Low
Use of IOP‐lowering medications ‐ 24 months · macular edema in diabetes
It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes use of IOP‐lowering medications ‐ 24 months compared with sham (very low certainty).
1 finding from 1 review
RR 21.6 [1.32, 354.7]
Studies not reported
Very low
Surgery for glaucoma ‐ 24 months · macular edema in diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in visual acuity (logMAR) ‐ 12 months (negative is better) · macular edema in diabetes
It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes change in visual acuity (logMAR) ‐ 12 months (negative is better) compared with macular laser (very low certainty).
1 finding from 1 review
MD 0.02
Studies not reported
Very low
Gain 3+ lines of visual acuity at 1 year · macular edema in diabetes
Intravitreal triamcinolone acetonide injection 4 mg showed no clear difference in gain of three or more lines visual acuity ‐ 12 months compared with macular laser (low certainty).
1 finding from 1 review
RR 0.85 [0.55, 1.3]
Studies not reported
Low
Change in retinal thickness (micron) (negative is better) · macular edema in diabetes
It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes change in retinal thickness (micron) (negative is better) compared with macular laser (very low certainty).
1 finding from 1 review
MD 5
Studies not reported
Very low
Cataract progression · macular edema in diabetes
Intravitreal triamcinolone acetonide injection 4 mg probably leads to higher cataract progression ‐ 9 to 24 months compared with macular laser (moderate certainty).
1 finding from 1 review
RR 2.68 [2.21, 3.24]
Studies not reported
Moderate
Use of IOP‐lowering medications · macular edema in diabetes
Intravitreal triamcinolone acetonide injection 4 mg probably leads to higher use of IOP‐lowering medications ‐ 9 to 24 months compared with macular laser (moderate certainty).
1 finding from 1 review
RR 3.92 [2.59, 5.96]
Studies not reported
Moderate
Change in retinal thickness (micron) (negative is better) · macular edema in diabetes
1 finding from 1 review
Surgery for glaucoma ‐ 24 months · macular edema in diabetes
Intravitreal triamcinolone acetonide injection 4 mg showed no clear difference in surgery for glaucoma ‐ 9 to 24 months compared with macular laser (low certainty).
1 finding from 1 review
RR 11.68 [0.63, 216]
Studies not reported
Low
Change in visual acuity (logMAR) ‐ 12 months (negative is better) · macular edema in diabetes
1 finding from 1 review
Gain of 3 or more lines of visual acuity · macular edema in diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Central retinal thickness μm (CRT) change at 1 year The aim of treatment is to reduce central retinal thickness so thinner is better. · macular edema in diabetes
It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes change in central retinal thickness (micron) ‐ 12 months (negative… compared with antiVEGF (very low certainty).
1 finding from 1 review
Cataract progression · macular edema in diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Use of IOP‐lowering medications · macular edema in diabetes
1 finding from 1 review
no estimate extracted
Studies not reported
Low