Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,494 questions · 1,521 findings · 132 reviews · Hepato-Biliary

No studies found 303 · 19.9%GRADE not reported 39 · 2.6%Very low 876 · 57.6%Low 216 · 14.2%Moderate 65 · 4.3%High 22 · 1.4%

L‐ornithine L‐aspartate vs lactulose

Non‐serious adverse events assessed using ICH‐GCP · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes non‐serious adverse events assessed using ICH‐GCP compared with lactulose (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs probiotic

All‐cause mortality · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes mortality compared with probiotic (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs probiotic

Hepatic encephalopathy · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes hepatic encephalopathy assessed based on neurocognitive manifestations compared with probiotic (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs probiotic

Serious adverse events assessed using ICH‐GCP · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes serious adverse events assessed using ICH‐GCP compared with probiotic (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs probiotic

Quality of life assessed using questionnaires · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

The review found no eligible studies for this question.

1 finding from 1 review

L‐ornithine L‐aspartate vs probiotic

Non‐serious adverse events assessed using ICH‐GCP · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

The review found no eligible studies for this question.

1 finding from 1 review

L‐ornithine L‐aspartate vs rifaximin

All‐cause mortality · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes mortality compared with rifaximin (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs rifaximin

Hepatic encephalopathy · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes hepatic encephalopathy assessed based on neurocognitive manifestations compared with rifaximin (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs rifaximin

Serious adverse events assessed using ICH‐GCP · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes serious adverse events assessed using ICH‐GCP compared with rifaximin (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs rifaximin

Quality of life assessed using questionnaires · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

The review found no eligible studies for this question.

1 finding from 1 review

L‐ornithine L‐aspartate vs placebo or no intervention

Hepatic encephalopathy

It is very uncertain whether L‐ornithine L aspartate changes hepatic encephalopathy assessed based on neurocognitive manifestations compared with placebo or no intervention (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs rifaximin

Non‐serious adverse events assessed using ICH‐GCP · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes non‐serious adverse events assessed using ICH‐GCP compared with rifaximin (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs placebo or no intervention

Serious adverse events assessed using ICH‐GCP

It is very uncertain whether L‐ornithine L aspartate changes serious adverse events assessed using ICH‐GCP compared with placebo or no intervention (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs placebo or no intervention

Non‐serious adverse events assessed using ICH‐GCP

It is very uncertain whether L‐ornithine L aspartate changes non‐serious adverse events assessed using ICH‐GCP compared with placebo or no intervention (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs lactulose

All‐cause mortality · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes mortality compared with lactulose (very low certainty).

1 finding from 1 review