Relapse during intervention defined as admission to inpatient therapeutic care, remain wasted, and dropouts during intervention period · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial
Standard ready‐to‐use therapeutic food (RUTF) leads to lower relapse during intervention defined as admission to inpatient… compared with RUTF using an alternative formulation (high certainty).
1 finding from 1 review
Mortality during intervention · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial
Standard ready‐to‐use therapeutic food (RUTF) showed no clear difference in mortality during intervention compared with RUTF using an alternative formulation (moderate certainty).
1 finding from 1 review
Rate of weight gain (g/kg/day) · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial
1 finding from 1 review
Relapse during intervention defined as admission to inpatient therapeutic care or recurrence of oedema or systematic infections during the study period, and dropouts during intervention period · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial
It is very uncertain whether standard ready‐to‐use therapeutic food (RUTF) provided at a dose… changes relapse during intervention defined as admission to inpatient… compared with an alternative dietary approach (very low certainty).
1 finding from 1 review
Mortality during intervention · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial
It is very uncertain whether standard ready‐to‐use therapeutic food (RUTF) provided at a dose… changes mortality during intervention compared with an alternative dietary approach (very low certainty).
1 finding from 1 review
Rate of weight gain (g/kg/day) · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial
1 finding from 1 review
Recovery during intervention defined as WHZ > 0 in 1 study; 100% weight for height in 1 study · children aged 6 months‐5 years with SAM (1 study included HIV‐uninfected children; 1 study included HIV‐infected children), all of whom…
Standard ready‐to‐use therapeutic food (RUTF) provided at a dose… may leads to higher recovery during intervention defined as WHZ > 0 in 1 study; 100%… compared with as a supplement to the usual diet (low certainty).
1 finding from 1 review
Relapse during intervention defined as admission to inpatient therapeutic care or recurrence of oedema or systematic infections during the study period, and dropouts during intervention period · children aged 6 months‐5 years with SAM (1 study included HIV‐uninfected children; 1 study included HIV‐infected children), all of whom…
Standard ready‐to‐use therapeutic food (RUTF) provided at a dose… may leads to lower relapse during intervention defined as admission to inpatient… compared with as a supplement to the usual diet (low certainty).
1 finding from 1 review
Mortality during intervention · children aged 6 months‐5 years with SAM (1 study included HIV‐uninfected children; 1 study included HIV‐infected children), all of whom…
It is very uncertain whether standard ready‐to‐use therapeutic food (RUTF) provided at a dose… changes mortality during intervention compared with as a supplement to the usual diet (very low certainty).
1 finding from 1 review
Rate of weight gain (g/kg/day) · children aged 6 months‐5 years with SAM (1 study included HIV‐uninfected children; 1 study included HIV‐infected children), all of whom…
1 finding from 1 review
Recovery during intervention defined as weight gain ≥ 15% in relation to baseline weight, absence of complications and oedema, and MUAC > 110 mm in 2 studies; MUAC > 12.4 cm without oedema in 1 study; WHZ ≥ 80% for two consecutive visits in 1 stud... · children aged 6 months‐5 years with SAM (and mixed HIV comorbidity), some of whom had been stabilised as inpatients pre‐trial
Standard ready‐to‐use therapeutic food (RUTF) showed no clear difference in recovery during intervention defined as weight gain ≥ 15% in… compared with RUTF using an alternative formulation (high certainty).
1 finding from 1 review
Anaemia · adolescent and adult menstruating women
Intermittent iron supplementation (alone or with any other… may leads to lower anaemia (haemoglobin concentration below a cut‐off defined by the… compared with no supplementation or placebo (low certainty).
1 finding from 1 review
Iron deficiency (as defined by trialists) · adolescent and adult menstruating women
It is very uncertain whether intermittent iron supplementation changes iron deficiency (as defined by the trialists using indicators of… compared with daily iron supplementation (very low certainty).
1 finding from 1 review
Ferritin (µg/L) · adolescent and adult menstruating women
1 finding from 1 review
Iron deficiency anaemia · adolescent and adult menstruating women
1 finding from 1 review
All‐cause morbidity · adolescent and adult menstruating women
1 finding from 1 review
Side effects or other adverse events · adolescent and adult menstruating women
Intermittent iron supplementation may leads to lower any adverse side effects compared with daily iron supplementation (low certainty).
1 finding from 1 review
Haemoglobin (g/dL) · adolescent and adult menstruating women
1 finding from 1 review
Iron deficiency (as defined by trialists) · adolescent and adult menstruating women
Intermittent iron supplementation (alone or with any other… showed no clear difference in iron deficiency (as defined by trialists by using indicators of iron… compared with no supplementation or placebo (low certainty).
1 finding from 1 review
Ferritin (µg/L) · adolescent and adult menstruating women
1 finding from 1 review