Findings

What do systematic reviews say?

1,060 questions · 1,105 findings · 84 reviews · Metabolic and Endocrine Disorders

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No studies found 434 · 39.3%GRADE not reported 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%

Intervention not reported

Health‐related quality of life · people at risk for development of T2DM

The review found no eligible studies for this question.

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Socioeconomic effects · people at risk for development of T2DM

The review found no eligible studies for this question.

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

All‐cause mortality · people at risk for development of T2DM

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2281 participants
Very low

Intervention not reported

Incidence of T2DM Definition/description: 1 trial established the diagnosis of T2DM defined as HbA1c ≥ 6.5%, or fasting plasma glucose ≥ 7.0 mmol/L, or 2‐hour plasma glucose post‐challenge (oral glucose tolerance test) ≥ 11.1 mmol/L (SCALE). Other... · people at risk for development of T2DM

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2243 participants
Very low

Intervention not reported

Change in BMI (kg/m²) · children (aged 6 to 11 years) being overweight or obese

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age… 2017 · Cochrane Headline outcomes only
no estimate extracted
24 studies · 2785 participants
Low

Intervention not reported

Adverse events (serious adverse events) · children (aged 6 to 11 years) being overweight or obese

The intervention showed no clear difference in adverse events (serious adverse events) (low certainty).

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age… 2017 · Cochrane Headline outcomes only
RR 0.57 [0.17, 1.93]
31 studies · 4096 participants
Low

Intervention not reported

Change in health‐related quality of life (SMD) Parent‐reported measures Instruments: PedsQL parent proxy: 23 items that yield total, physical summary, and psychosocial summary scores, each with a possible range of 0‐100 (100 = best possible health... · children (aged 6 to 11 years) being overweight or obese

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age… 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 718 participants
Very low

Intervention not reported

All‐cause mortality · children (aged 6 to 11 years) being overweight or obese

The review found no eligible studies for this question.

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Morbidity · children (aged 6 to 11 years) being overweight or obese

The review found no eligible studies for this question.

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Socioeconomic effects · children (aged 6 to 11 years) being overweight or obese

The review found no eligible studies for this question.

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

a) Change in BMI · adolescents (aged 12‐17 years) being overweight or obese

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to… 2017 · Cochrane Headline outcomes only
no estimate extracted
28 studies · 2774 participants
Moderate

Intervention not reported

Adverse events · adolescents (aged 12‐17 years) being overweight or obese

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

Health‐related quality of life Validated self‐reported measures · adolescents (aged 12‐17 years) being overweight or obese

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to… 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 972 participants
Low

Intervention not reported

All‐cause mortality · adolescents (aged 12‐17 years) being overweight or obese

The review found no eligible studies for this question.

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Morbidity · adolescents (aged 12‐17 years) being overweight or obese

The review found no eligible studies for this question.

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Socioeconomic effects · adolescents (aged 12‐17 years) being overweight or obese

The review found no eligible studies for this question.

1 finding from 1 review

Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

All‐cause mortality

The review found no eligible studies for this question.

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Diabetes‐related morbidity

The review found no eligible studies for this question.

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Health‐related quality of life

The review found no eligible studies for this question.

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Patient satisfaction

The review found no eligible studies for this question.

1 finding from 1 review

Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with type 2… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found