Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,494 questions · 1,521 findings · 132 reviews · Hepato-Biliary

No studies found 303 · 19.9%GRADE not reported 39 · 2.6%Very low 876 · 57.6%Low 216 · 14.2%Moderate 65 · 4.3%High 22 · 1.4%

Intervention not reported

Aldosterone antagonists plus loop diuretics (1 RCT; 41 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (1 RCT; 41 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (4 RCTs; 145 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (4 RCTs; 145 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (2 RCT; 84 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (2 RCT; 84 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (1 RCT; 31 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (1 RCT; 31 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (1 RCT; 25 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (1 RCT; 25 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Transjugular intrahepatic portosystemic shunt (6 RCTs; 427 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes transjugular intrahepatic portosystemic shunt (6 RCTs; 427… (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (3 RCTs; 125 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (3 RCTs; 125 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Transjugular intrahepatic portosystemic shunt (6 RCTs; 392 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes transjugular intrahepatic portosystemic shunt (6 RCTs; 392… (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (4 RCTs; 211 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (4 RCTs; 211 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus paracentesis plus fluid replacement (1 RCT; 36 participants) · people with liver cirrhosis and ascites

The intervention may leads to higher aldosterone antagonists plus paracentesis plus fluid replacement (1… (low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (4 RCTs; 242 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (4 RCTs; 242 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (3 RCTs; 114 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (3 RCTs; 114 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (5 RCTs; 165 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (5 RCTs; 165 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics plus paracentesis plus fluid replacement (No direct RCT) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus paracentesis plus… (very low certainty).

1 finding from 1 review

Intervention not reported

Transjugular intrahepatic portosystemic shunt (7 RCTs; 452 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes transjugular intrahepatic portosystemic shunt (7 RCTs; 452… (very low certainty).

1 finding from 1 review