Findings

What do systematic reviews say?

4,860 questions · 64,864 findings · 4,913 reviews · Headline outcomes only

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No studies found 13,869 · 21.4%GRADE not reported 3,491 · 5.4%Very low 16,300 · 25.1%Low 17,338 · 26.7%Moderate 10,900 · 16.8%High 2,966 · 4.6%

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Summary of findings table ‐ Multimodal interventions vs usual care

Total nocturnal sleep time (minutes) · sleep disturbances in dementia

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 272 participants
Low

Summary of findings table ‐ Light therapy vs usual care

Sleep efficiency · sleep disturbances in dementia

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 133 participants
Very low

Summary of findings table ‐ Multimodal interventions vs usual care

Consolidated sleep ‐ not measured · sleep disturbances in dementia

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Multimodal interventions vs usual care

Sleep efficiency · sleep disturbances in dementia

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 485 participants
Very low

Summary of findings table ‐ Multimodal interventions vs usual care

Total wake time at night (minutes) · sleep disturbances in dementia

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 102 participants
Low

Summary of findings table ‐ Multimodal interventions vs usual care

Number of nocturnal awakenings · sleep disturbances in dementia

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 404 participants
Low

Summary of findings table ‐ Multimodal interventions vs usual care

Sleep onset latency ‐ not reported · sleep disturbances in dementia

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Multimodal interventions vs usual care

Adverse events · sleep disturbances in dementia

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 589 participants
Low

Summary of findings table ‐ Light therapy vs usual care

Total wake time at night (minutes) · sleep disturbances in dementia

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 205 participants
Very low

Summary of findings table ‐ Light therapy vs usual care

Number of nocturnal awakenings · sleep disturbances in dementia

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 136 participants
Very low

Summary of findings table ‐ Light therapy vs usual care

Sleep onset latency ‐ not reported · sleep disturbances in dementia

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 3 participants
Low

Summary of findings table ‐ Light therapy vs usual care

Adverse events · sleep disturbances in dementia

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 318 participants
Very low

Summary of findings table ‐ Physical activities vs usual care

Total nocturnal sleep time (minutes) · sleep disturbances in dementia

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 167 participants
Low

Summary of findings table ‐ Physical activities vs usual care

Consolidated sleep ‐ not measured · sleep disturbances in dementia

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for sleep disturbances in people with dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ataluren vs placebo

Quality of life: CFQ‐R respiratory domain: absolute change from baseline · adults and children with CF with at least one class I mutation (PTC)

1 finding from 1 review

Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 506 participants
High

Ataluren vs placebo

FEV1 % predicted: relative change from baseline · adults and children with CF with at least one class I mutation (PTC)

1 finding from 1 review

Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 203 participants
High

Ataluren vs placebo

Adverse events relating to treatment Scale: mild, moderate, severe and total · adults and children with CF with at least one class I mutation (PTC)

1 finding from 1 review

Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 517 participants
Moderate

Ataluren vs placebo

Pulmonary exacerbations · adults and children with CF with at least one class I mutation (PTC)

1 finding from 1 review

Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 232 participants
High

Ataluren vs placebo

Nutrition and growth Change in: a) weight (kg) b) BMI (kg/m2) c) height (m) · adults and children with CF with at least one class I mutation (PTC)

1 finding from 1 review

Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 506 participants
High

Ataluren vs placebo

Sweat chloride level ‐ change from baseline Scale: mmol/L · adults and children with CF with at least one class I mutation (PTC)

1 finding from 1 review

Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 194 participants
High