Intervention not reported
Adverse events (serious ‐ resulting in hospitalisation or death) · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments
1 finding from 1 review
Intervention not reported
Revision, re‐operation, or treatment failure · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments
It is very uncertain whether the intervention changes revision, re‐operation, or treatment failure (very low certainty).
1 finding from 1 review
Intervention not reported
Change in pain Visual Analog Scale (VAS) at 12 weeks (0 to 10 scale; lower score means less pain) · people with rheumatoid arthritis
It is very uncertain whether the intervention changes change in pain Visual Analog Scale (VAS) at 12 weeks (0 to 10 scale;… (very low certainty).
1 finding from 1 review
Intervention not reported
Change in measure of disease activity Disease Activity Score (DAS‐28‐ESR) at 12 weeks (0 to 10 score; lower score means less disease activity) · people with rheumatoid arthritis
It is very uncertain whether the intervention changes change in measure of disease activity Disease Activity Score… (very low certainty).
1 finding from 1 review
Intervention not reported
Change in function Health Assessment Questionnaire (HAQ) at 12 weeks (0 to 3 score; lower score means better function) · people with rheumatoid arthritis
It is very uncertain whether the intervention changes change in function Health Assessment Questionnaire (HAQ) at 12 weeks… (very low certainty).
1 finding from 1 review
Intervention not reported
Radiographic progression · people with rheumatoid arthritis
The review found no eligible studies for this question.
1 finding from 1 review
Intervention not reported
Short‐term serious adverse events · people with rheumatoid arthritis
The review found no eligible studies for this question.
1 finding from 1 review
Intervention not reported
Long‐term adverse effects or toxicity · people with rheumatoid arthritis
The review found no eligible studies for this question.
1 finding from 1 review
Intervention not reported
Withdrawals – overall (at 8 to 12 weeks) · people with rheumatoid arthritis
The intervention may leads to lower withdrawals – overall (at 8 to 12 weeks) (low certainty).
1 finding from 1 review
Outcomesa · Patients with osteoarthritis of the knee or hip
The review found no eligible studies for this question.
1 finding from 1 review
Number of participants reporting an adverse event · patients with osteoarthritis
Tramadol in combination with acetaminophen probably leads to higher number of participants experiencing any adverse event compared with placebo (moderate certainty).
1 finding from 1 review
Withdrawals due to adverse events · patients with osteoarthritis
Tramadol in combination with acetaminophen may leads to higher number of participants who withdrew due to adverse events compared with placebo (low certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · patients with osteoarthritis
1 finding from 1 review
Outcomesa · patients with osteoarthritis
The review found no eligible studies for this question.
1 finding from 1 review
Pain · patients with osteoarthritis
1 finding from 1 review
Physical function · patients with osteoarthritis
The review found no eligible studies for this question.
1 finding from 1 review
Number of participants reporting an adverse event · patients with osteoarthritis
The review found no eligible studies for this question.
1 finding from 1 review
Withdrawals due to adverse events · patients with osteoarthritis
It is very uncertain whether tramadol alone changes number of participants who withdrew due to adverse events compared with acetaminophen (very low certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · patients with osteoarthritis
The review found no eligible studies for this question.
1 finding from 1 review
Outcomesa · patients with osteoarthritis
The review found no eligible studies for this question.
1 finding from 1 review