MortalityNumber of participants: 285(2 RCTs) WGET 2005 · adults (age 18 years and older) with GPA ANCA‐associated vasculitis or microscopic polyangiitis (only a subset of patients in one study,…
Active drug (etanercept or belimumab) with standard therapy showed no clear difference in mortalityNumber of participants: 285(2 RCTs) WGET 2005 compared with standard therapy with placebo (low certainty).
1 finding from 1 review
Any measure of 'substantial' pain relief · rotator cuff disease
Shock wave therapy showed no clear difference in pain relief > 50%a compared with placebo (low certainty).
1 finding from 1 review
Pain Multiple scalese translated to VAS 0–10 (10 was severe pain)f · rotator cuff disease
Shock wave therapy showed no clear difference in pain Multiple scalese translated to VAS 0–10 (10 was severe pain)f compared with placebo (moderate certainty).
1 finding from 1 review
Functional outcomes · rotator cuff disease
Shock wave therapy probably leads to higher function Multiple scalese translated to Constant 0–100 scale (100… compared with placebo (moderate certainty).
1 finding from 1 review
Participant‐reported success · rotator cuff disease
Shock wave therapy showed no clear difference in participant‐reported success compared with placebo (low certainty).
1 finding from 1 review
Quality of life · rotator cuff disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participant withdrawals due to adverse events or treatment intolerance · rotator cuff disease
Shock wave therapy showed no clear difference in number of participant withdrawals due to adverse events or treatment… compared with placebo (low certainty).
1 finding from 1 review
Number of participants reporting an adverse event · rotator cuff disease
Shock wave therapy may leads to higher number of participants experiencing any adverse event compared with placebo (low certainty).
1 finding from 1 review
Pain on movement at 24 hours Visual analogue scale Scale from zero to 10
1 finding from 1 review
Functional outcomes
1 finding from 1 review
Global assessment of treatment success
Knee replacement with tourniquet showed no clear difference in global assessment of success Participants reporting overall… compared with knee replacement without tourniquet (low certainty).
1 finding from 1 review
Health‐related quality of life (mental)
1 finding from 1 review
Serious adverse events
Knee replacement with tourniquet probably leads to higher serious adverse events compared with knee replacement without tourniquet (moderate certainty).
1 finding from 1 review
Cognitive function
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Survival of the implant Risk of revision At 1 year
It is very uncertain whether knee replacement with tourniquet changes survival of the implant Risk of revision At 1 year compared with knee replacement without tourniquet (very low certainty).
1 finding from 1 review
Intervention not reported
Pain · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments
1 finding from 1 review
Intervention not reported
Function · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments
1 finding from 1 review
Intervention not reported
Participant‐rated global assessment of treatment success · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Quality of life · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments
1 finding from 1 review
Intervention not reported
Adverse events (total): · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments
It is very uncertain whether the intervention changes adverse events (total): (very low certainty).
1 finding from 1 review