What do systematic reviews say?

Single‐incision slings vs transobturator minimally‐invasive slings

Single‐incision slings leads to lower number of women with mesh exposure, extrusion or erosion in any area compared with transobturator minimally‐invasive slings (high certainty).

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  RR 0.61 [0.39, 0.96]
  16 studies · 2378 participants
  High

Single‐incision slings vs transobturator minimally‐invasive slings

Single‐incision slings probably leads to lower number of women with urinary retention compared with transobturator minimally‐invasive slings (moderate certainty).

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  RR 0.68 [0.47, 0.97]
  23 studies · 2891 participants
  Moderate

Single‐incision slings vs autologous fascial slings

The review found no eligible studies for this question.

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Single‐incision slings vs transobturator minimally‐invasive slings

Single‐incision slings may leads to higher quality of life: at 12 months compared with transobturator minimally‐invasive slings (low certainty).

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  SMD 0.24 [0.09, 0.39]
  8 studies · 689 participants
  Low

Single‐incision slings vs transobturator minimally‐invasive slings

Single‐incision slings showed no clear difference in number of women requiring repeat continence surgery or mesh revision compared with transobturator minimally‐invasive slings (low certainty).

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  RR 1.42 [0.94, 2.16]
  13 studies · 1460 participants
  Low

Single‐incision slings vs autologous fascial slings

Single‐incision slings showed no clear difference in number of women with dyspareunia compared with autologous fascial slings (low certainty).

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  RR 1.33 [0.32, 5.53]
  1 study · 70 participants
  Low

Single‐incision slings vs autologous fascial slings

Single‐incision slings showed no clear difference in number of women with mesh exposure, extrusion or erosion in any area compared with autologous fascial slings (low certainty).

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  RR 2 [0.19, 21.06]
  1 study · 70 participants
  Low

Single‐incision slings vs autologous fascial slings

The review found no eligible studies for this question.

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Single‐incision slings vs autologous fascial slings

The review found no eligible studies for this question.

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Single‐incision slings vs autologous fascial slings

The review found no eligible studies for this question.

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Single‐incision slings vs retropubic minimally‐invasive slings

Single‐incision slings showed no clear difference in subjective cure or improvement of urinary incontinence: at 12 months compared with retropubic minimally‐invasive slings (low certainty).

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  RR 0.99 [0.91, 1.07]
  2 studies · 297 participants
  Low

Single‐incision slings vs retropubic minimally‐invasive slings

The review found no eligible studies for this question.

• Single‐incision sling operations for urinary incontinence in women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

The review found no eligible studies for this question.

• Anti‐vascular endothelial growth factor for proliferative diabetic retinopathy 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

• Anti‐vascular endothelial growth factor for proliferative diabetic retinopathy 2023 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 1172 participants
  Moderate

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without… probably leads to higher complete regression of new vessels (dichotomous outcome) compared with PRP alone (moderate certainty).

• Anti‐vascular endothelial growth factor for proliferative diabetic retinopathy 2023 · Cochrane Headline outcomes only
  RR 1.63 [1.19, 2.24]
  5 studies · 405 participants
  Moderate

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

• Anti‐vascular endothelial growth factor for proliferative diabetic retinopathy 2023 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 189 participants
  Low

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without… probably leads to lower presence of vitreous haemorrhaged compared with PRP alone (moderate certainty).

• Anti‐vascular endothelial growth factor for proliferative diabetic retinopathy 2023 · Cochrane Headline outcomes only
  RR 0.72 [0.57, 0.9]
  6 studies · 1008 participants
  Moderate

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without… may leads to lower need for vitrectomy compared with PRP alone (low certainty).

• Anti‐vascular endothelial growth factor for proliferative diabetic retinopathy 2023 · Cochrane Headline outcomes only
  RR 0.67 [0.49, 0.93]
  8 studies · 1248 participants
  Low

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

• Anti‐vascular endothelial growth factor for proliferative diabetic retinopathy 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 382 participants
  Low

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

• Anti‐vascular endothelial growth factor for proliferative diabetic retinopathy 2023 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 1070 participants
  Very low