Findings

What do systematic reviews say?

4,317 questions · 75,239 findings · 5,342 reviews

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No studies found 15,213 · 20.2%GRADE not reported 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

PGD2R antagonist OC000459 vs placebo

Withdrawals due to adverse events · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 26 participants
Very low

Swallowed fluticasone vs prednisone

Clinical improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes clinical improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 1.09 [0.9, 1.33]
1 study · 80 participants
Very low

Swallowed fluticasone vs prednisone

Clinical improvement (continuous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Swallowed fluticasone vs prednisone

Histological improvement at 4 weeks (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes histological improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 1.1 [0.87, 1.38]
1 study · 80 participants
Very low

Swallowed fluticasone vs prednisone

Histological improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 68 participants
Very low

Corticosteroids vs placebo

Histological improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 449 participants
Low

Swallowed fluticasone vs prednisone

Endoscopic improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes endoscopic improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 1.13 [0.91, 1.41]
1 study · 80 participants
Very low

Swallowed fluticasone vs prednisone

Endoscopic improvement (continuous) · active EoE pediatric patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Swallowed fluticasone vs prednisone

Withdrawals due to adverse events · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes withdrawals due to adverse events at 4 weeks compared with oral prednisone (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.5 [0.16, 1.53]
1 study · 80 participants
Very low

Oral viscous budesonide vs swallowed fluticasone

Clinical improvement (dichotomous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral viscous budesonide vs swallowed fluticasone

Clinical improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 84 participants
Low

Oral viscous budesonide vs swallowed fluticasone

Histological improvement (dichotomous) · active EoE patients

Oral viscous budesonide showed no clear difference in histological improvement at study endpoint (dichotomous) compared with swallowed fluticasone (low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 1.13 [0.84, 1.51]
1 study · 129 participants
Low

Oral viscous budesonide vs swallowed fluticasone

Histological improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 111 participants
Low

Oral viscous budesonide vs swallowed fluticasone

Endoscopic improvement (dichotomous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral viscous budesonide vs swallowed fluticasone

Endoscopic improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 111 participants
Low

Oral viscous budesonide vs swallowed fluticasone

Withdrawals due to adverse events · active EoE patients

Oral viscous budesonide showed no clear difference in withdrawals due to adverse events at 8 weeks compared with swallowed fluticasone (low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.98 [0.42, 2.32]
1 study · 129 participants
Low

Corticosteroids vs placebo

Endoscopic improvement (dichotomous) · active EoE patients

Corticosteroids showed no clear difference in endoscopic improvement (dichotomous) compared with placebo (low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 2.6 [0.82, 8.19]
3 studies · 102 participants
Low

Esomeprazole vs fluticasone

Clinical improvement (dichotomous) · active EoE patients

The review found no eligible studies for this question.

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Esomeprazole vs fluticasone

Clinical improvement (continuous) · active EoE patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 67 participants
Very low

Esomeprazole vs fluticasone

Histological improvement (dichotomous) · active EoE patients

It is very uncertain whether esomeprazole changes histological improvement at 8 weeks (dichotomous) compared with fluticasone (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 1.62 [0.77, 3.41]
2 studies · 72 participants
Very low