Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,923 questions · 1,956 findings · 143 reviews · Musculoskeletal

No studies found 555 · 28.4%GRADE not reported 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

NSAID injection vs glucocorticoid injection

Resolution at 12 to 24 weeks Quinell Grade (range 0 to 4, resolved disease is grade 0) · adults (> 18 years of age) with trigger finger

NSAID injection showed no clear difference in resolution at 12 to 24 weeks Quinell Grade (range 0 to 4, resolved… compared with glucocorticoid injection (low certainty).

1 finding from 1 review

Active drug (etanercept or belimumab) with standard therapy vs placebo + standard care

Remission · adults (age 18 years and older) with GPA ANCA‐associated vasculitis or microscopic polyangiitis (only a subset of patients in one study,…

Active drug (etanercept or belimumab) with standard therapy showed no clear difference in remission (number of patients with remission) compared with standard therapy with placebo (low certainty).

1 finding from 1 review