Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

962 questions · 1,000 findings · 69 reviews · Urology

No studies found 196 · 19.6%GRADE not reported 33 · 3.3%Very low 198 · 19.8%Low 354 · 35.4%Moderate 206 · 20.6%High 13 · 1.3%

Injectional nicardipine vs Normal saline

Treatment‐related adverse effects · men with chronic Peyronie's disease (plaques without calcification)

It is very uncertain whether injectional nicardipine changes treatment‐related adverse effects compared with saline (very low certainty).

1 finding from 1 review

Potassium paraaminobenzoate vs placebo

Patient‐reported ability to have intercourse · men with acute (maximum of 12 months) Peyronie's disease with no prior treatment and no evidence of calcified plaques (pain during…

Potassium paraaminobenzoate showed no clear difference in patient‐reported ability to have intercourse compared with placebo (low certainty).

1 finding from 1 review

Injectional collagenase vs placebo

Outcomes ( · men with Peyronie's disease (diagnosis of disease: at least 12 months, penile curvature: at least 30 degrees)

The review found no eligible studies for this question.

2 findings from 1 review