Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,556 questions · 10,375 findings · 429 reviews · All outcomes

No studies found 1,344 · 13%GRADE not reported 6,832 · 65.9%Very low 1,228 · 11.8%Low 613 · 5.9%Moderate 290 · 2.8%High 68 · 0.7%

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Counter-stimulation or distraction vs Conventional treatment

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Clinical examination with 24-month recall vs Clinical examination with 6-month recall

Oral health behaviour (1-9 scale) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with 24-month recall showed no clear difference in oral health behaviour (1-9 scale) compared with clinical examination with 6-month recall; GRADE not reported.

1 finding from 1 review

Video modelling acclimatisation vs Acclimatisation in clinic (tell-show-do)

Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Combination system (Isolite) vs Conventional dental suction (low-volume evacuator / saliva ejector)

Reduction in contamination of aerosols (CFU) after ultrasonic scaling / AGP · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether combination system (Isolite) changes reduction in contamination of aerosols (CFU) after ultrasonic… compared with saliva ejector (low-volume evacuator) (very low certainty).

1 finding from 1 review

Video modelling acclimatisation vs Acclimatisation in clinic (tell-show-do)

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Clinical examination with 24-month recall vs Clinical examination with 12-month recall

Dental caries: dmfs increment (primary teeth) · Regular-attending primary-care dental patients aged 3, 16 or 18 years at entry (aged up to 20; low caries risk)

It is very uncertain whether clinical examination with 24-month recall changes dental caries: dmfs increment (primary teeth) compared with clinical examination with 12-month recall (very low certainty).

1 finding from 1 review

Intervention not reported

Dental caries in permanent teeth · Children (permanent dentition) worldwide

In Europe, the pooled prevalence of permanent-teeth caries in children was 44.1% (95% CI 36.1 to 52.5); certainty not graded.

1 finding from 1 review

Clinical examination with 24-month recall vs Clinical examination with 6-month recall

Cost (healthcare-system perspective): total cost per patient (GBP) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with 24-month recall showed no clear difference in cost (healthcare-system perspective): total cost per patient (GBP) compared with clinical examination with 6-month recall; GRADE not reported.

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Plaque index (PI) / oral hygiene · Critically ill patients (adults and children) receiving mechanical ventilation in ICU
1 finding from 1 review

Intraglandular botulinum neurotoxin (BoNT) injection vs No BoNT (placebo or pre-treatment baseline)

Development of >=1 new carious lesion (caries incidence) · Patients with drooling (sialorrhea) due to neurological disease

In one RCT, BoNT-B 2500 U was not associated with a statistically significant increase in new caries versus placebo (RR 2.4, 95% CI 0.48 to 11.80; not significant).

2 findings from 1 review