Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,119 questions · 2,206 findings · 117 reviews · Common Mental Disorders

No studies found 387 · 17.5%GRADE not reported 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%

SSRI antidepressants vs tricyclic antidepressants (TCAs)

Drop‐out Objective · Adults with mental disorders in low‐ and middle‐income countries

It is very uncertain whether SSRI antidepressants changes drop‐outs (12 weeks) compared with TCA (very low certainty).

1 finding from 1 review

Metformin vs placebo

Fasting blood glucose (mg/dL) · Adults with mental disorders in low‐ and middle‐income countries
2 findings from 1 review

Discontinuation by "tapering" vs usual family planning care

Relapse · participants with depressive or anxiety disorders

It is very uncertain whether discontinuation by "tapering" changes relapse (as defined by study authors) (HR) compared with continuation (or usual care) (very low certainty).

1 finding from 1 review

Discontinuation by "tapering" vs usual family planning care

Adverse events · participants with depressive or anxiety disorders

It is very uncertain whether discontinuation by "tapering" changes adverse events compared with continuation (or usual care) (very low certainty).

1 finding from 1 review