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What do systematic reviews say?

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Evidence found and GRADE certainty

4,811 questions · 70,850 findings · 5,139 reviews

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No studies found 15,174 · 21.4%GRADE not reported 6,479 · 9.1%Very low 17,330 · 24.5%Low 17,814 · 25.1%Moderate 11,056 · 15.6%High 2,997 · 4.2%

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Swallowed fluticasone vs prednisone

Clinical improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes clinical improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Swallowed fluticasone vs prednisone

Histological improvement at 4 weeks (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes histological improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Swallowed fluticasone vs prednisone

Endoscopic improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes endoscopic improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Swallowed fluticasone vs prednisone

Withdrawals due to adverse events · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes withdrawals due to adverse events at 4 weeks compared with oral prednisone (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Endoscopic improvement (dichotomous) · active EoE patients

Corticosteroids showed no clear difference in endoscopic improvement (dichotomous) compared with placebo (low certainty).

1 finding from 1 review