Periodontal healing at 48 months · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether thymosin alpha 1 (10-minute soak prior to replantation) changes periodontal healing at 48 months compared with control (saline) (very low certainty).
1 finding from 1 review
Relief of pain · Adults over 18 years presenting with a single tooth with a clinical diagnosis of irreversible pulpitis
The review found no eligible studies for this question.
1 finding from 1 review
Periodontal healing at 12 months · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether ledermix root canal medicament (day 0 to 10) changes periodontal healing at 12 months (tooth level) compared with ultracal root canal medicament (day 7 to 10) (very low certainty).
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Glutaraldehyde + zinc oxide and eugenol (ZOE) showed no clear difference in clinical failure compared with full strength formocresol (FC); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Metapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with endoflas chlorophenol free (Endoflas-CF); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Low-level laser therapy (LLLT) + calcium hydroxide showed no clear difference in radiological failure compared with formocresol (FC); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Biodentine showed no clear difference in clinical failure compared with calcium hydroxide (CH); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) probably leads to higher radiological failure compared with formocresol (FC) (moderate certainty).
2 findings from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Mineral trioxide aggregate (MTA) may leads to lower radiological failure compared with calcium hydroxide (CH) (low certainty).
2 findings from 1 review
RR 0.12 [0.04, 0.36]
4 studies · 150 participants
Low
No radiological failure in any participant; not estimable
1 study · 50 participants
GRADE not reported
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Ferric sulphate/MTA pulpotomy showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE) pulpectomy; GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether diode laser changes clinical failure compared with electrosurgery (very low certainty).
1 finding from 1 review
Ferric sulphate (FS) + mineral trioxide aggregate (MTA) vs Mineral trioxide aggregate (MTA)
Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Assessed pain, soft tissue pathology, mobility, radiolucency, root resorption, pulp canal obliteration (Doyle 2010); no clinical/radiological failure outcome; no significant differences
1 study · 130 participants
GRADE not reported
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Ferric sulphate (FS) showed no clear difference in radiological failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes clinical failure compared with calcium hydroxide (CH) (very low certainty).
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in radiological failure compared with glutaraldehyde + zinc oxide and eugenol (ZOE); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in clinical failure compared with full strength formocresol (FC); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether mineral trioxide aggregate (MTA) changes clinical failure compared with 3Mixtatin (very low certainty).
1 finding from 1 review