Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

671 questions · 731 findings · 61 reviews · Drugs and Alcohol

No studies found 57 · 7.8%GRADE not reported 39 · 5.3%Very low 186 · 25.4%Low 239 · 32.7%Moderate 171 · 23.4%High 39 · 5.3%

Interpersonal Psychotherapy for Depression (IPT‐D) vs Other Psychological Interventions

Substance use ‐ relapse · co‐occurring depression and substance use disorders

It is very uncertain whether interpersonal Psychotherapy for Depression (IPT‐D) changes substance use ‐ relapse compared with other Psychological Interventions (very low certainty).

1 finding from 1 review

Interpersonal Psychotherapy for Depression (IPT‐D) vs Other Psychological Interventions

Retention in treatment · co‐occurring depression and substance use disorders

It is very uncertain whether interpersonal Psychotherapy for Depression (IPT‐D) changes treatment retention compared with other Psychological Interventions (very low certainty).

1 finding from 1 review

Integrated CBT vs Twelve Step Facilitation

Percent of days abstinent · co‐occurring depression and substance use disorders
2 findings from 1 review

Interpersonal Psychotherapy for Depression (IPT‐D) vs Other Psychological Interventions

Depression score · co‐occurring depression and substance use disorders
2 findings from 1 review

Motivational interviewing/mindfulness and cognitive skills vs waiting list control

Abstinence from drug use · drug‐using offenders with co‐occurring mental health problems

Motivational interviewing/mindfulness and cognitive skills showed no clear difference in abstinence from drug use compared with waiting list control (low certainty).

1 finding from 1 review

Multi‐systemic therapy involving family and juveniles vs treatment

Arrested · drug‐using offenders with co‐occurring mental health problems

Multi‐systemic therapy involving family and juveniles showed no clear difference in arrested assessed by corroborating with police data compared with treatment (low certainty).

1 finding from 1 review