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Evidence found and GRADE certainty

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Misoprostol in abdominal myomectomy · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in misoprostol in abdominal myomectomy compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Peri‐cervical tourniquet vs no treatment to reduce blood loss during myomectomy

Blood loss (ml) Estimated blood loss during myomectomy · women with uterine fibroids

Peri‐cervical tourniquet showed no clear difference in blood loss (ml) Estimated blood loss during myomectomy compared with no treatment to reduce blood loss during myomectomy (low certainty).

1 finding from 1 review

Peri‐cervical tourniquet vs no treatment to reduce blood loss during myomectomy

Blood transfusion · women with uterine fibroids

Peri‐cervical tourniquet may leads to lower need for blood transfusion Participants who received blood transfusion compared with no treatment to reduce blood loss during myomectomy (low certainty).

1 finding from 1 review

Peri‐cervical tourniquet vs no treatment to reduce blood loss during myomectomy

Operating time · women with uterine fibroids

It is very uncertain whether peri‐cervical tourniquet changes duration of surgery (min) Operative time compared with no treatment to reduce blood loss during myomectomy (very low certainty).

1 finding from 1 review

Gelatin‐thrombin matrix vs placebo or no treatment to reduce blood loss during myomectomy

Blood loss (ml) Estimated blood loss during myomectomy · women with uterine fibroids

Gelatin‐thrombin matrix showed no clear difference in blood loss (ml) Estimated blood loss during myomectomy compared with placebo or no treatment to reduce blood loss during myomectomy (low certainty).

1 finding from 1 review

Gelatin‐thrombin matrix vs placebo or no treatment to reduce blood loss during myomectomy

Blood transfusion · women with uterine fibroids

Gelatin‐thrombin matrix may leads to lower need for blood transfusion Participants who received blood transfusion compared with placebo or no treatment to reduce blood loss during myomectomy (low certainty).

1 finding from 1 review

Ascorbic acid vs no treatment to reduce blood loss during myomectomy

Blood loss (ml) Estimated blood loss during myomectomy · women with uterine fibroids

Ascorbic acid showed no clear difference in blood loss (ml) Estimated blood loss during myomectomy compared with no treatment to reduce blood loss during myomectomy (low certainty).

1 finding from 1 review

Ascorbic acid vs no treatment to reduce blood loss during myomectomy

Blood transfusion · women with uterine fibroids

It is very uncertain whether ascorbic acid changes need for blood transfusion Participants who received blood transfusion compared with no treatment to reduce blood loss during myomectomy (very low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Misoprostol in laparoscopic myomectomy · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in misoprostol in laparoscopic myomectomy compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Bupivicaine plus epinephrine · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in bupivicaine plus epinephrine compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Intravenous injection of tranexamic acid · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in intravenous injection of tranexamic acid compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Gelatin‐thrombin matrix · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in gelatin‐thrombin matrix compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Dinoprostone (prostaglandin E2 analogue) · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in dinoprostone (prostaglandin E2 analogue) compared with placebo or no treatment (low certainty).

1 finding from 1 review