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Transvaginal permanent mesh probably leads to higher mesh exposure compared with native tissue repair (moderate certainty).
Transvaginal permanent mesh probably leads to higher bladder function compared with native tissue repair (moderate certainty).
Transvaginal permanent mesh showed no clear difference in painful intercourse ‐ de novo dyspareunia compared with native tissue repair (moderate certainty).
It is very uncertain whether transvaginal permanent mesh changes quality of life compared with native tissue repair (very low certainty).
Transvaginal biological graft showed no clear difference in awareness of prolapse (1 to 3 years) compared with native tissue repair (moderate certainty).
It is very uncertain whether summary of findings table ‐ Metformin changes regression of endometrial hyperplasia (with or without atypia) to… compared with megestrol (very low certainty).
It is very uncertain whether summary of findings table ‐ Metformin + megestrol changes progression of endometrial hyperplasia to endometrial cancer compared with megestrol (very low certainty).
It is very uncertain whether summary of findings table ‐ Metformin + megestrol changes hysterectomy rate compared with megestrol (very low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
It is very uncertain whether summary of findings table ‐ Metformin + levonorgestrel (intrauterine… changes regression of endometrial hyperplasia (with or without atypia) to… compared with levonorgestrel intrauterine system (very low certainty).
The review found no eligible studies for this question.
It is very uncertain whether summary of findings table ‐ Metformin + levonorgestrel (intrauterine… changes hysterectomy rate compared with levonorgestrel intrauterine system (very low certainty).
It is very uncertain whether summary of findings table ‐ Metformin + levonorgestrel (intrauterine… changes abnormal uterine bleeding compared with levonorgestrel intrauterine system (very low certainty).
It is very uncertain whether summary of findings table ‐ Metformin + levonorgestrel (intrauterine… changes adverse effects during treatment ‐ all effects compared with levonorgestrel intrauterine system (very low certainty).
It is very uncertain whether summary of findings table ‐ Metformin + levonorgestrel (intrauterine… changes adverse effects during treatment ‐ nausea compared with levonorgestrel intrauterine system (very low certainty).
It is very uncertain whether summary of findings table ‐ Metformin + levonorgestrel (intrauterine… changes adverse effects during treatment ‐ heaviness in lower abdomen compared with levonorgestrel intrauterine system (very low certainty).