Findings

What do systematic reviews say?

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

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No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Intervention not reported

Perineal trauma · pregnant women (women with pre‐existing type 1 or type 2 diabetes are NOT included)

It is very uncertain whether the intervention changes perineal trauma (very low certainty).

1 finding from 1 review

Antenatal dietary supplementation with myo‐inositol for preventing gestational diabetes 2023 · Cochrane Headline outcomes only
RR 4 [0.45, 35.25]
1 study · 234 participants
Very low

Intervention not reported

Postnatal depression · pregnant women (women with pre‐existing type 1 or type 2 diabetes are NOT included)

1 finding from 1 review

Antenatal dietary supplementation with myo‐inositol for preventing gestational diabetes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Development of subsequent type 2 diabetes mellitus · pregnant women (women with pre‐existing type 1 or type 2 diabetes are NOT included)

1 finding from 1 review

Antenatal dietary supplementation with myo‐inositol for preventing gestational diabetes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Large‐for‐gestational age · infants of pregnant women

The intervention showed no clear difference in large‐for‐gestational age (low certainty).

1 finding from 1 review

Antenatal dietary supplementation with myo‐inositol for preventing gestational diabetes 2023 · Cochrane Headline outcomes only
RR 1.4 [0.65, 3.02]
1 study · 234 participants
Low

Intervention not reported

Perinatal mortality (stillbirth and neonatal mortality) · infants of pregnant women

1 finding from 1 review

Antenatal dietary supplementation with myo‐inositol for preventing gestational diabetes 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (maternal outcomes)

Hypertensive disorders of pregnancy · women with gestational diabetes mellitus

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in hypertensive disorders of pregnancy (including pre‐eclampsia,… compared with less‐tight glycaemic targets (maternal outcomes) (low certainty).

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
RR 1.16 [0.8, 1.69]
2 studies · 1491 participants
Low

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Death or serious morbidity composite · Children (as neonate, child, adult) of women with GDM

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in composite of mortality or serious morbidity (as defined by trial) compared with less‐tight glycaemic targets (child (as neonate, child, adult)… (low certainty).

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
RR 0.84 [0.55, 1.29]
3 studies · 1559 participants
Low

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Neurosensory disability · Children (as neonate, child, adult) of women with GDM

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Infant hypoglycaemia · Children (as neonate, child, adult) of women with GDM

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in infant hypoglycaemia compared with less‐tight glycaemic targets (child (as neonate, child, adult)… (moderate certainty).

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
RR 0.92 [0.72, 1.18]
3 studies · 1556 participants
Moderate

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Adiposity · Children (as neonate, child, adult) of women with GDM

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Diabetes · Children (as neonate, child, adult) of women with GDM

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (maternal outcomes)

Development of type 2 diabetes · women with gestational diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (maternal outcomes)

Caesarean section · women with gestational diabetes mellitus

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
0.98 [0.82, 1.17]
3 studies · 1662 participants
Moderate

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (maternal outcomes)

Return to pre‐pregnancy weight · women with gestational diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (maternal outcomes)

Induction of labour · women with gestational diabetes mellitus

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in induction of labour compared with less‐tight glycaemic targets (maternal outcomes) (moderate certainty).

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
RR 0.96 [0.78, 1.18]
1 study · 1096 participants
Moderate

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (maternal outcomes)

Perineal trauma · women with gestational diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (maternal outcomes)

Postnatal depression · women with gestational diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Perinatal mortality · Children (as neonate, child, adult) of women with GDM

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1499 participants
Low

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Large‐for‐gestational age · Children (as neonate, child, adult) of women with GDM

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in large‐for‐gestational‐age compared with less‐tight glycaemic targets (child (as neonate, child, adult)… (moderate certainty).

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
RR 0.96 [0.72, 1.29]
3 studies · 1556 participants
Moderate

Intervention not reported

Perinatal death · women with an abnormal cardiotocograph (CTG) in labour

1 finding from 1 review

Fetal scalp stimulation for assessing fetal well‐being during labour 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
GRADE not reported