Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Dental caries

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No studies found 0 · 0%GRADE not reported 1 · 50%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Cleft lip and/or palate (CL/P) vs Healthy controls without cleft

Probing pocket depth · Individuals assessed for periodontal health (mainly children and adolescents, age >2 years)

Persons with orofacial cleft have a greater probing pocket depth than healthy controls (MD 0.88, 95% CI 0.82 to 0.95; low certainty).

1 finding from 1 review

Oral health in patients with cleft lip and palate: a systematic literature review and meta-analysis of periodontal and… 2025 All outcomes
Clinical dental examination; various countries (e.g., Brazil, India, China, Thailand, USA)
MD 0.88 [0.82, 0.95]
3 studies · 340 participants
Low

Metal-free implant abutments (zirconia) vs Metal implant abutments (titanium)

Implant probing pocket depth (PPD) · Adults (18 years or older) with one missing tooth in the aesthetic zone needing an implant-supported single crown

Metal-free implant abutments (zirconia) showed no clear difference in implant probing pocket depth (PPD) compared with metal implant abutments (titanium); GRADE not reported.

1 finding from 1 review

Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes
12 months
MD -0.22 [-0.60, 0.16]
2 studies · 47 participants
GRADE not reported