Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

39 questions · 44 findings · 6 reviews

No studies found 4 · 9.1%GRADE not reported 24 · 54.5%Very low 3 · 6.8%Low 11 · 25%Moderate 2 · 4.5%High 0 · 0%

Early treatment (two-phase: phase 1 in childhood, phase 2 in adolescence) with functional appliance vs Late treatment (one-phase in adolescence) with functional appliance

Final overjet · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase: phase 1 in childhood, phase 2 in… led to lower final overjet compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.

2 findings from 1 review

Removable functional appliance vs Fixed functional appliance

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Removable functional appliance may leads to higher final overjet compared with fixed functional appliance (low certainty).

1 finding from 1 review

Early treatment (two-phase) with headgear vs Late treatment (one-phase in adolescence) with headgear

Final overjet · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear showed no clear difference in final overjet compared with late treatment (one-phase in adolescence) with headgear (low certainty).

2 findings from 1 review

Twin Block functional appliance vs Modified Twin Block appliances

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Twin Block functional appliance (conventional) showed no clear difference in final overjet compared with modified Twin Block appliances; GRADE not reported.

1 finding from 1 review

Fixed functional appliance (FORSUS FRD) vs Intermaxillary elastics

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Fixed functional appliance (FORSUS FRD) showed no clear difference in final overjet compared with intermaxillary elastics; GRADE not reported.

1 finding from 1 review

Early treatment (two-phase) with headgear vs Early treatment (two-phase) with functional appliance

Final overjet · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear showed no clear difference in final overjet compared with early treatment (two-phase) with functional appliance; GRADE not reported.

2 findings from 1 review

Activator functional appliance vs Fixed functional appliance (FORSUS FRD EZ)

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Activator functional appliance led to higher final overjet compared with fixed functional appliance (FORSUS FRD EZ); GRADE not reported.

1 finding from 1 review

Late treatment (one-phase) with removable functional appliance vs no treatment

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Late treatment (one-phase) with removable functional appliance may leads to lower final overjet compared with no treatment (low certainty).

1 finding from 1 review

Twin Block functional appliance vs Other functional appliances (Bionator, Herbst, R-appliance, Dynamax, Bite-Jumping)

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Twin Block functional appliance showed no clear difference in final overjet compared with other functional appliances (Bionator, Herbst, R-appliance, Dynamax,… (low certainty).

1 finding from 1 review

FMA stepwise advancement (SWG) vs FMA single step advancement (SSG)

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

FMA stepwise advancement (SWG) showed no clear difference in final overjet compared with FMA single step advancement (SSG); GRADE not reported.

1 finding from 1 review

Late treatment (one-phase) with fixed functional appliance vs no treatment

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Late treatment (one-phase) with fixed functional appliance may leads to lower final overjet compared with no treatment (low certainty).

1 finding from 1 review

Harvold Activator vs Frankel function regulator

Occlusion (net change in overjet, short term) · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Harvold Activator led to lower overjet change compared with frankel function regulator; GRADE not reported.

1 finding from 1 review

Intraoral distalising appliance vs Headgear (extraoral appliance)

Overjet · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…

Intraoral distalising appliance may leads to higher change in overjet (mm) compared with headgear (extraoral appliance) (low certainty).

1 finding from 1 review

Intraoral distalising appliance vs Another (different) intraoral distalising appliance

Overjet · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…
1 finding from 1 review

Orthodontic distalising appliance (intraoral or extraoral) vs no intervention

Overjet · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…
1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Residual overjet at the end of treatment · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

The review found no eligible studies for this question.

1 finding from 1 review

Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)

Residual overjet at the end of treatment · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to adults up to 48-54 years)

The review found no eligible studies for this question.

1 finding from 1 review

Orthodontic appliances (palatal crib) vs no treatment

Occlusion (net change in overjet, short term) · Children with a non-nutritive sucking habit (digit or pacifier)
1 finding from 1 review
  • Table 1 (reduction in malocclusion), Villa 1997 (n=24), palatal crib vs no treatment: net change in overjet (mm) - no treatment 0.02; palatal crib -0.2; no statistically significant net change in overjet between…
    1 study · 24 participants
    GRADE not reported