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Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 3 reviews · Neuromuscular

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 20%Low 0 · 0%Moderate 4 · 80%High 0 · 0%

Intervention not reported

Major adverse events · for effects on cramps, people (other than pregnant women) with muscle cramps (largely older adults); for adverse events, all populations

It is very uncertain whether the intervention changes major adverse events (very low certainty).

1 finding from 1 review

Quinine vs placebo

Major adverse events · patients with muscle cramps
1 finding from 1 review
  • Quinine for muscle cramps 2015 · Cochrane Headline outcomes only
    no estimate extracted
    18 studies · 1103 participants
    Moderate

Corticosteroids vs placebo

Adverse events Assessed as: occurrence of one or more major adverse events requiring withdrawal of treatment · people with nerve damage (< 6 months' duration) in leprosy

Corticosteroids showed no clear difference in adverse events Assessed as: occurrence of one or more major adverse… compared with placebo (moderate certainty).

1 finding from 1 review