Adverse events · Adults with periodontitis (chronic and aggressive)
Metronidazole + SRP showed no clear difference in adverse events compared with amoxicillin + metronidazole + SRP; GRADE not reported.
1 finding from 1 review
All three included trials (Matarazzo 2008; Silva 2011; Xajigeorgiou 2006) reported adverse events in both MTZ + SRP and AMOX + MTZ + SRP groups (nausea, vomiting, diarrhoea, headache, metallic taste, irritability, mild…
3 studies · 84 participants
GRADE not reported
Adverse events · Adults with aggressive periodontitis
Amoxicillin + metronidazole + SRP showed no clear difference in adverse events compared with clarithromycin + SRP; GRADE not reported.
1 finding from 1 review
Adverse events · Adults with chronic periodontitis
Moxifloxacin + SRP showed no clear difference in adverse events compared with SRP; GRADE not reported.
1 finding from 1 review
Adverse events · Adults with periodontitis (chronic and aggressive)
Clarithromycin + SRP showed no clear difference in adverse events compared with SRP; GRADE not reported.
1 finding from 1 review
Adverse events · Adults with chronic periodontitis
Levofloxacin + SRP showed no clear difference in adverse events compared with SRP; GRADE not reported.
1 finding from 1 review
Adverse events · Adults with chronic periodontitis
Cefixime + SRP showed no clear difference in adverse events compared with SRP; GRADE not reported.
1 finding from 1 review
The only included trial (Dukic 2016) reported nausea, dizziness and/or anorexia in the cefixime + SRP group.
1 study · 60 participants
GRADE not reported
Adverse events · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether metronidazole + SRP changes adverse events compared with SRP (very low certainty).
1 finding from 1 review
Adverse events · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · Patients with active mild to moderate ulcerative colitis
Oral 5‐ASA probably leads to lower adverse events compared with SASP (moderate certainty).
1 finding from 1 review
Adverse events · Patients with active mild to moderate ulcerative colitis
Once daily dosing showed no clear difference in adverse events compared with conventional dosing (moderate certainty).
1 finding from 1 review
Adverse events · Patients with active mild to moderate ulcerative colitis
Oral 5‐ASA showed no clear difference in adverse events compared with comparator 5‐ASA (moderate certainty).
1 finding from 1 review
Adverse events · Patients with active mild to moderate ulcerative colitis
Oral 5‐ASA showed no clear difference in adverse events compared with placebo (high certainty).
1 finding from 1 review
Adverse events · Patients with quiescent ulcerative colitis
Oral 5‐aminosalicylic acid showed no clear difference in adverse events compared with placebo (moderate certainty).
1 finding from 1 review
Adverse events · women having gynaecological surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · women during gynaecological surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · women after gynaecological surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · women having gynaecological surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · heavy menstrual bleeding
LNG‐IUS probably leads to higher adverse events compared with endometrial ablation (moderate certainty).
1 finding from 1 review
Adverse events · heavy menstrual bleeding
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · heavy menstrual bleeding
LNG‐IUS probably leads to lower adverse events compared with any other medical treatment (moderate certainty).
1 finding from 1 review