Summary of findings table ‐ Metformin + megestrol vs megestrol
Adverse effects during treatment · endometrial hyerplasia
1 finding from 1 review
- no estimate extracted1 study · 8 participantsVery low
Findings
What do systematic reviews say?
6 questions · 6 findings · 1 reviews · Gynaecology and Fertility
No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 5 · 83.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Summary of findings table ‐ Metformin + levonorgestrel (intrauterine system) vs levonorgestrel intrauterine system
Adverse events: nausea · endometrial hyperplasia
It is very uncertain whether summary of findings table ‐ Metformin + levonorgestrel (intrauterine… changes adverse effects during treatment ‐ nausea compared with levonorgestrel intrauterine system (very low certainty).
1 finding from 1 review
- OR 5.11 [1.21, 21.68]1 study · 51 participantsVery low
Summary of findings table ‐ Metformin + levonorgestrel (intrauterine system) vs levonorgestrel intrauterine system
Adverse effects during treatment ‐ all effects · endometrial hyperplasia
It is very uncertain whether summary of findings table ‐ Metformin + levonorgestrel (intrauterine… changes adverse effects during treatment ‐ all effects compared with levonorgestrel intrauterine system (very low certainty).
1 finding from 1 review
- OR 4 [1.15, 13.9]1 study · 51 participantsVery low
Metformin vs megestrol
Adverse effects during treatment ‐ not reported · endometrial hyperplasia
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Summary of findings table ‐ Metformin + levonorgestrel (intrauterine system) vs levonorgestrel intrauterine system
Adverse effects during treatment ‐ pain in abdomen · endometrial hyperplasia
It is very uncertain whether summary of findings table ‐ Metformin + levonorgestrel (intrauterine… changes adverse effects during treatment ‐ pain in abdomen compared with levonorgestrel intrauterine system (very low certainty).
1 finding from 1 review
- OR 0.83 [0.22, 3.18]1 study · 51 participantsVery low
Summary of findings table ‐ Metformin + levonorgestrel (intrauterine system) vs levonorgestrel intrauterine system
Adverse effects during treatment ‐ heaviness in lower abdomen · endometrial hyperplasia
It is very uncertain whether summary of findings table ‐ Metformin + levonorgestrel (intrauterine… changes adverse effects during treatment ‐ heaviness in lower abdomen compared with levonorgestrel intrauterine system (very low certainty).
1 finding from 1 review
- OR 1.38 [0.32, 5.85]1 study · 51 participantsVery low