Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,949 questions · 1,994 findings · 636 reviews

No studies found 504 · 25.3%GRADE not reported 340 · 17.1%Very low 477 · 23.9%Low 390 · 19.6%Moderate 241 · 12.1%High 42 · 2.1%

Cyclosporin plus prednisolone vs prednisolone

Adverse effects: number needing cytotoxic agents · SSNS in children

It is very uncertain whether cyclosporin plus prednisolone changes adverse effects: number needing cytotoxic agents compared with prednisolone alone (very low certainty).

1 finding from 1 review

RISPERIDONE vs placebo

Adverse events including extrapyramidal effects · terminally ill adults with delirium

Summary of findings: risperidone showed no clear difference in adverse events including extrapyramidal effectsd compared with placebo (low certainty).

1 finding from 1 review

Summary of findings: lorazepam plus haloperidol vs placebo plus haloperidol

Adverse events including extrapyramidal effects · terminally ill adults with severe delirium

It is very uncertain whether summary of findings: lorazepam plus haloperidol changes adverse events including extrapyramidal effectsd compared with placebo plus haloperidol (very low certainty).

1 finding from 1 review