What do systematic reviews say?

Vaginal surgery with mesh vs non‐mesh repair

Vaginal surgery with mesh showed no clear difference in awareness of prolapse compared with without mesh (moderate certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 1.08 [0.35, 3.3]
  1 study · 54 participants
  Moderate

Vaginal surgery with mesh vs non‐mesh repair

Vaginal surgery with mesh showed no clear difference in surgery for recurrent prolapse compared with without mesh (moderate certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 0.57 [0.3, 1.06]
  5 studies · 450 participants
  Moderate

Vaginal surgery with mesh vs non‐mesh repair

Vaginal surgery with mesh showed no clear difference in prolapse on examination (Stage 2 or above) ‐ Any recurrent prolapse compared with without mesh (low certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 0.36 [0.09, 1.4]
  3 studies · 269 participants
  Low

Vaginal surgery with mesh vs non‐mesh repair

Vaginal surgery with mesh showed no clear difference in bladder injury compared with without mesh (low certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 3 [0.91, 9.89]
  4 studies · 445 participants
  Low

Vaginal surgery with mesh vs non‐mesh repair

Vaginal surgery with mesh may leads to higher mesh exposure compared with without mesh (low certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 14.75 [4.64, 46.89]
  5 studies · 499 participants
  Low

Vaginal surgery with mesh vs non‐mesh repair

Vaginal surgery with mesh showed no clear difference in bladder function ‐ Stress incontinence compared with without mesh (moderate certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 1.37 [0.97, 1.93]
  6 studies · 463 participants
  Moderate

Vaginal surgery with mesh vs non‐mesh repair

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 180 participants
  Moderate