Findings

What do systematic reviews say?

557 questions · 600 findings · 75 reviews

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No studies found 188 · 31.3%GRADE not reported 62 · 10.3%Very low 154 · 25.7%Low 122 · 20.3%Moderate 62 · 10.3%High 12 · 2%

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Preterm birth < 32 weeks · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, polishing, or… changes preterm birth < 32 weeks compared with no treatment (very low certainty).

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
RR 1.35 [0.78, 2.32]
3 studies · 2755 participants
Very low

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Low birth weight < 1500 g · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, polishing, or… changes low birth weight < 1500 g compared with no treatment (very low certainty).

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
RR 0.80 [0.38, 1.70]
2 studies · 2550 participants
Very low

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Severe pre-eclampsia (progression from mild pre-eclampsia) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, polishing, or… changes severe pre-eclampsia (progression from mild pre-eclampsia) compared with no treatment (very low certainty).

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
RR 1.21 [0.77, 1.92]
1 study · 60 participants
Very low

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Mean birth weight · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
Eight studies (5120 participants) reported birth weight in grams; data not pooled due to skewness; mean difference ranged between -52.8 and 476.6 grams.
8 studies · 5120 participants
GRADE not reported

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Percentage of bleeding on probing (BOP) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
Reported as a secondary periodontal outcome (Analysis 1.9); results not meta-analysed due to considerable heterogeneity (I2 91% to 100%); reduction in favour of periodontal treatment.
6 studies
GRADE not reported

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Perinatal mortality · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, polishing, or… changes perinatal mortality (including fetal and neonatal deaths up to the… compared with no treatment (very low certainty).

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
RR 0.85 [0.51, 1.43]
7 studies · 5320 participants
Very low

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Attachment change · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
Reported as a secondary periodontal outcome (Analysis 1.7); results not meta-analysed due to considerable heterogeneity (I2 91% to 100%); reduction in favour of periodontal treatment.
4 studies
GRADE not reported

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Change in probing pocket depth (PPD) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
Reported as a secondary periodontal outcome (Analysis 1.6); results not meta-analysed due to considerable heterogeneity (I2 91% to 100%); reduction in favour of periodontal treatment.
4 studies
GRADE not reported

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Small‐for‐gestational age · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

Periodontal treatment (scaling and root planing, polishing, or… showed no clear difference in small for gestational age compared with no treatment (low certainty).

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
RR 0.97 [0.81, 1.16]
3 studies · 3610 participants
Low

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Low birth weight (< 2.5 kg) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

Periodontal treatment (scaling and root planing, polishing, or… may leads to lower birth weight (low birth weight < 2500 g) compared with no treatment (low certainty).

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
RR 0.67 [0.48, 0.95]
7 studies · 3470 participants
Low

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Maternal death · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
0% in both groups; Not estimated; 2134 participants (4 RCTs)
4 studies · 2134 participants
GRADE not reported

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Plaque index (PI) / oral hygiene · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
Reported as a secondary periodontal outcome (Analysis 1.8); results not meta-analysed due to considerable heterogeneity (I2 91% to 100%); reduction in favour of periodontal treatment.
2 studies
GRADE not reported

Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs no treatment

Pre‐eclampsia · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, polishing, or… changes pre-eclampsia compared with no treatment (very low certainty).

1 finding from 1 review

Treating periodontal disease for preventing adverse birth outcomes in pregnant women 2017 · Cochrane All outcomes
RR 1.10 [0.74, 1.62]
3 studies · 2946 participants
Very low

Any topical or systemic intervention (topical/systemic steroids, ciclosporin, tacrolimus, retinoids, anti-malarials, biologics, phototherapy, surgery) vs Placebo, no treatment, another active intervention, or a different dose of the same intervention

Eating a normally varied diet · People of any age with erosive lichen planus affecting the oral, anogenital, and/or oesophageal regions

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for erosive lichen planus affecting mucosal sites 2012 · Cochrane All outcomes
No studies reported this outcome.
0 studies
No studies found

Any topical or systemic intervention (topical/systemic steroids, ciclosporin, tacrolimus, retinoids, anti-malarials, biologics, phototherapy, surgery) vs Placebo, no treatment, another active intervention, or a different dose of the same intervention

Restoration of sexual activity · People of any age with erosive lichen planus affecting the oral, anogenital, and/or oesophageal regions

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for erosive lichen planus affecting mucosal sites 2012 · Cochrane All outcomes
None of the included studies assessed the effectiveness of treatments of genital ELP; thus, this outcome was not reported.
0 studies
No studies found

Any topical or systemic intervention (topical/systemic steroids, ciclosporin, tacrolimus, retinoids, anti-malarials, biologics, phototherapy, surgery) vs Placebo, no treatment, another active intervention, or a different dose of the same intervention

Reduction in number of flares · People of any age with erosive lichen planus affecting the oral, anogenital, and/or oesophageal regions

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for erosive lichen planus affecting mucosal sites 2012 · Cochrane All outcomes
No studies reported this outcome.
0 studies
No studies found

Any topical or systemic intervention (topical/systemic steroids, ciclosporin, tacrolimus, retinoids, anti-malarials, biologics, phototherapy, surgery) vs Placebo, no treatment, another active intervention, or a different dose of the same intervention

Reduction in severity of flares · People of any age with erosive lichen planus affecting the oral, anogenital, and/or oesophageal regions

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for erosive lichen planus affecting mucosal sites 2012 · Cochrane All outcomes
No studies reported this outcome.
0 studies
No studies found