Single dose primaquine at 0.75 mg/kg vs no primaquine, with artemisinin partner,: Participants with gametocytes at day 3‐4, by PCR
Single dose primaquine at 0.75 mg/kg showed no clear difference in participants with gametocytes at day 3‐4, by PCR compared with no primaquine, with artemisinin partner, (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Single dose primaquine at 0.75 mg/kg vs no primaquine, with artemisinin partner, Participants with gametocytes at day 3‐4, by PCR · adults and children with malaria being treated with artemisinin combination treatment Single dose primaquine at 0.75 mg/kg showed no clear difference in participants with gametocytes at day 3‐4, by PCR compared with no primaquine, with artemisinin partner, (low certainty). Primaquine or other 8‐aminoquinolines for reducing Plasmodium falciparum transmission (2018) · Cochrane Headline outcomes only | RR 0.92 [0.75, 1.13] | 2 studies · 290 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Primaquine or other 8‐aminoquinolines for reducing Plasmodium falciparum transmission 2018 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.