Question · asked by 1 review

CMC spray / HCC spray / HCC gel vs Liquid margarine (and between each other): Dry mouth (xerostomia)

Population
Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy, haemodialysis)
Intervention
CMC spray / HCC spray / HCC gel
Comparison
Liquid margarine (and between each other)
Outcome
Dry mouth (xerostomia)

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
CMC spray / HCC spray / HCC gel vs Liquid margarine (and between each other)
Xerostomia (median oral dryness) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's…
Interventions for the management of dry mouth: topical therapies (2011) · Cochrane All outcomes
Furumoto 1998 (crossover, n=28, medians/IQR): median day-10 oral dryness (lower = less dry): CMC spray 28.00 (3.06), HCC spray 28.75 (2.23), HCC gel 27.75 (3.62), margarine 29.25 (5.06). Only HCC gel showed a…1 study · 28 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for the management of dry mouth: topical therapies
2011 · Cochrane All outcomes
2011-10Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.