Question · asked by 1 review

Summary of findings: Comparison 3 ‐ deferiprone (DFP) vs deferasirox (DFX): All‐cause mortality (n/N)

Population
Not specified
Intervention
Summary of findings: Comparison 3 ‐ deferiprone (DFP)
Comparison
deferasirox (DFX)
Outcome
All‐cause mortality (n/N)

Summary of findings: Comparison 3 ‐ deferiprone (DFP) showed no clear difference in all‐cause mortality (n/N) compared with deferasirox (DFX) (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of findings: Comparison 3 ‐ deferiprone (DFP) vs deferasirox (DFX)
All‐cause mortality (n/N)
Summary of findings: Comparison 3 ‐ deferiprone (DFP) showed no clear difference in all‐cause mortality (n/N) compared with deferasirox (DFX) (low certainty).
Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or… (2023) · Cochrane Headline outcomes only
RD 01 study · 390 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia
2023 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.