Question · asked by 1 review
Extended prophylaxis vs placebo: VTE‐related mortality4
- Population
- patients with unprovoked venous thromboembolism
- Intervention
- Extended prophylaxis
- Comparison
- placebo
- Outcome
- VTE‐related mortality4
Extended prophylaxis showed no clear difference in VTE‐related mortalitya compared with placebo (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Extended prophylaxis vs placebo VTE‐related mortalitya · patients with unprovoked venous thromboembolism Extended prophylaxis showed no clear difference in VTE‐related mortalitya compared with placebo (low certainty). Secondary prevention of recurrent venous thromboembolism after initial oral anticoagulation therapy in… (2017) · Cochrane Headline outcomes only | OR 0.98 [0.14, 6.98] | 4 studies · 1862 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Secondary prevention of recurrent venous thromboembolism after initial oral anticoagulation therapy in patients with unprovoked venous… 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Extended prophylaxis vs another VTE extended prophylaxis · patients with unprovoked venous thromboembolism · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.