Question · asked by 1 review

Metformin vs placebo or no treatment: Weight: clinically important change in BMI (kg/m2)

Population
people with schizophrenia with antipsychotic‐induced weight gain
Intervention
Metformin
Comparison
placebo or no treatment
Outcome
Weight: clinically important change in BMI (kg/m2)

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Metformin vs placebo or no treatment
Weight: clinically important change in BMI (kg/m2) · people with schizophrenia with antipsychotic‐induced weight gain
Pharmacological interventions for prevention of weight gain in people with schizophrenia (2022) · Cochrane Headline outcomes only
no estimate extracted0 studies · 0 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pharmacological interventions for prevention of weight gain in people with schizophrenia
2022 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.