Question · asked by 1 review

Calcium supplementation/fortification vs placebo or no intervention: Gestational age (preterm birth < 37 weeks)

Population
healthy pregnant women receiving calcium supplementation vs placebo or no treatment
Intervention
Calcium supplementation/fortification
Comparison
placebo or no intervention
Outcome
Gestational age (preterm birth < 37 weeks)

Calcium supplementation showed no clear difference in preterm birth (a) Birth prior to 37 weeks compared with placebo or no treatment (maternal outcomes) (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Calcium supplementation vs placebo or no treatment (maternal outcomes)
Preterm birth (a) Birth prior to 37 weeks · healthy pregnant women receiving calcium supplementation vs placebo or no treatment
Calcium supplementation showed no clear difference in preterm birth (a) Birth prior to 37 weeks compared with placebo or no treatment (maternal outcomes) (moderate certainty).
Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and… (2015) · Cochrane Headline outcomes only
RR 0.86 [0.7, 1.05]13 studies · 16139 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
2015 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.