Question · asked by 1 review

Phosphodiesterase 4 inhibitors vs placebo: Lung function: FEV1 mL (change from baseline)

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Phosphodiesterase‐4 inhibitors vs placebo
Change in FEV₁ · people with stable chronic obstructive pulmonary disease
Phosphodiesterase‐4 inhibitors for chronic obstructive pulmonary disease (2020) · Cochrane Headline outcomes only
no estimate extracted29 studies · 20815 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Phosphodiesterase‐4 inhibitors for chronic obstructive pulmonary disease
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.